Effects of tDCS and VNS on Postoperative Analgesia
Unknown statusNot applicableNCT06554067
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
This study seeks to evaluate the efficacy of transcranial direct current stimulation (tDCS) and Afferent Vagus nerve simulation (VNS) in treating acute postoperative pain of patients in the post-anesthesia care unit after general surgery. Study outcomes will include changes in pain levels and vital signs. For patients who are admitted after surgery, opioid consumption in the 24 hours after surgery and time from surgery to discharge are recorded as secondary outcomes. Patients will be divided in the following comparison groups: * Group +/+ will receive ten minutes of active tDCS followed by ten minutes of active VNS. * Group +/- will receive ten minutes of active tDCS followed by ten minutes of sham VNS. * Group -/+ will receive ten minutes of sham tDCS followed by ten minutes of active VNS. * Group -/- will receive ten minutes of sham tDCS followed by ten minutes of sham VNS.
Study details
- Official title
- Effects of tDCS and VNS on Postoperative Analgesia
- Conditions
- Interventions
- Device: Active transcranial direct current stimulation
- Device: Active vagus nerve stimulation
- Other: Sham transcranial direct current stimulation
- Other: Sham vagus nerve stimulation
- Sponsor
- Columbia University
- Start date
- 2024-08
- Primary completion
- 2025-08
- Sex
- All
- Age range
- from 18 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Total sites listed
- 0
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Adults aged 18 years or above with the capacity to provide informed consent who are undergoing an elective surgery requiring general anesthesia Exclusion Criteria: * cardiac bradyarrhythmia: taking beta-blockers; * patients with metal implants around the chest, neck, or head (e.g. implantable pacemakers and defibrillators, deep brain stimulation devices); * pregnancy * history of epilepsy or seizures. * patients undergoing surgical procedures involving the head, neck or spine, or those requiring the use of cardiopulmonary bypass
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT06554067