PETMRI for Chronic Pain from Spinal or Peripheral Nerve Origin

Brief summary (from the registry)

The purpose of this study is to compare the uptake of \[18F\]FTC-146 in healthy volunteers to that of individuals suffering from chronic pain with Spinal or Peripheral Nerve Origin. Primary Objectives: A) To quantify the bio-distribution of \[18F\] FTC-146 uptake in subjects with Spinal or Peripheral Nerve Origin pain and compare it with healthy controls. B) To determine whether painful schwannomas can be differentiated from non-painful schwannomas based on imaging. Secondary Objectives: A) To assess the reproducibility of \[18F\]FTC-146 PET imaging within the same healthy volunteer subjects using Test-Retest analysis. B) To investigate whether post-treatment \[18F\]FTC-146 uptake differs from pre-treatment uptake and correlate the imaging with subject reported pain level after treatment

Study details

Official title

Use of (18F)FTC-146 PET_MRI for Characterizing Chronic Pain Phenotypes in Chronic Pain Patients with Spinal or Peripheral Nerve Origin

Conditions

• Nerve Pain
• Neuropathic Pain
• Nociceptive Pain
• MIxed Pain (Nociceptive and Neuropathic)

Interventions

• Drug: [18F]FTC-146

Sponsor

Stanford University

Start date

2024-10-01

Primary completion

2030-10-01

Sex

All

Age range

from 18 Years

Healthy volunteers

true

Results posted

No results posted in this snapshot

Total sites listed

0

Eligibility criteria