Ultrasound-Guided Injection vs Intramuscular Steroid for Carpal Tunnel Syndrome
CompletedNot applicableNCT06725420
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Carpal tunnel syndrome (CTS) is the most common and disability-causing entrapment neuropathy; however, a standardized protocol for first-line management has yet to be established. Different treatment approaches have their own positive and negative aspects. The aim of this study is to compare the effectiveness of ultrasound-guided local steroid injection and intramuscular steroid injection in mild-to-moderate CTS. Patients will be assessed for pain levels, functional/symptom status, hand-finger strength, side effects, patient satisfaction, median nerve ultrasonographic measurements, and EMG before and after treatment .
Study details
- Official title
- Comparison of the Effectiveness of Ultrasound-guided Local Steroid Injection vs Intramuscular Steroid Injection in the Treatment of Carpal Tunnel Syndrome: A Prospective, Randomized, Controlled, Single-blind Study
- Conditions
- Carpal Tunnel Syndrome (CTS)
- Chronic Pain
- Interventions
- Other: Ultrasound-guided local Injection
- Other: Intramuscular Steroid Injection
- Device: Splinting
- Sponsor
- Konya Beyhekim Training and Research Hospital
- Start date
- 2024-12-10
- Primary completion
- 2025-09-19
- Sex
- All
- Age range
- from 18 Years
- Results posted
- No results posted in this snapshot
- Countries
- Turkey (Türkiye)
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Age ≥18 years * Presence of typical CTS symptoms (numbness, tingling, paresthesias, or pain that may be provoked by nighttime or activity-related posture * VAS score of ≥ 3/10 * Symptom duration longer than 12 weeks * Positive Tinel's and/or Phalen's sign * Electrophysiologically mild or moderate CTS being diagnosed. * Volunteer to participate in study Exclusion Criteria: * Patients with shoulder, elbow, wrist, or finger problems (e.g., impingement syndrome, epicondylitis, history of fractures in the wrist, de Quervain's tenosynovitis, trigger finger, Complex Regional Pain Syndrome (CRPS), Dupuytren's contracture). * Patients with a history of trauma or surgery in the affected hand, or those with significant anatomical deformities. * Patients with systemic diseases such as rheumatological disorders, hypothyroidism, amyloidosis, diabetes, gout, or chronic kidney failure. * Patients with conditions that may mimic CTS, such as polyneuropathy, plexopathy, cervical radiculopathy, or thoracic outlet syndrome. * Patients with cognitive dysfunction or communication issues. * Patients with severe CTS, neurological deficits (e.g., thenar atrophy, muscle weakness in thumb abduction/opposition), or those requiring surgical intervention. * Patients who have received local steroid injections or physical therapy to the hand/wrist within the last 6 months. * Patients who are receiving or will receive another/additional treatment for CTS. * Pregnant or lactating women. * Patients with active malignancies or local/systemic infections. * Patients who are receiving any active treatment (e.g., NSAIDs, oral/intramuscular steroids, acupuncture, other pain medications). * Patients with upper extremity involvement due to first motor neuron damage (e.g., stroke-hemiplegia, tetraparesis, multiple sclerosis). * Patients with a bifid median nerve, persistent median artery, ganglion cyst, tenosynovitis, or tendinitis in the wrist. * Use of a wrist splint during the last 6 months. * Allergy to corticosteroids or local anesthetics, and blood diathesis
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT06725420