Long-Term Outcomes of Different Surgical Techniques for Sacral Tarlov Cysts: A Prospective Cohort Study
Not yet recruitingNCT06756984
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Brief Summary The goal of this observational study is to evaluate the long-term outcomes of different surgical techniques for sacral Tarlov cysts in adult patients aged 18-75 years diagnosed with symptomatic sacral Tarlov cysts. The main questions it aims to answer are: * Does one surgical technique result in better pain relief (measured by VAS score) and functional recovery (measured by JOA score) compared to others? * How do different surgical techniques impact the long-term recurrence rate and complication rate? Researchers will compare three surgical techniques: 1. Partial cyst wall resection with nerve root sleeve plasty. 2. Partial cyst wall resection with nerve root sleeve reinforcement and reconstruction. 3. Autologous fat/muscle with fibrin glue microscopic cyst filling. Participants will: * Undergo one of the three surgical procedures based on clinical indications. * Complete preoperative and postoperative assessments, including pain and functional scoring, as well as MRI evaluations at baseline and during follow-up. * Participate in a follow-up program for up to 2 years to monitor outcomes and recurrence.
Study details
- Official title
- A Prospective Cohort Study on the Long-Term Outcomes and Prognostic Factors of Different Surgical Techniques for the Treatment of Sacral Tarlov Cysts
- Conditions
- Sacral Tarlov Cysts
- Symptomatic Sacral Cysts
- Chronic Pain Related to Sacral Cysts
- Neurological Dysfunction Associated With Tarlov Cysts
- Interventions
- Procedure: Partial Cyst Wall Resection with Nerve Root Sleeve Plasty
- Procedure: Partial Cyst Wall Resection with Nerve Root Sleeve Reinforcement and Reconstruction:
- Procedure: Autologous Fat/Muscle with Fibrin Glue Microscopic Cyst Filling
- Sponsor
- Beijing Jishuitan Hospital
- Start date
- 2025-05-13
- Primary completion
- 2026-06-30
- Sex
- All
- Age range
- from 18 Years to 75 Years
- Results posted
- No results posted in this snapshot
- Total sites listed
- 0
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria 1. Age 18-75 years. 2. Diagnosed with symptomatic sacral Tarlov cysts confirmed by MRI. 3. Presence of at least one of the following symptoms: * Persistent sacral or lower back pain (VAS score ≥ 4). * Neurological deficits such as lower extremity numbness or weakness. * Bowel, bladder, or sexual dysfunction attributable to the cyst. 4. Eligible for surgical intervention based on clinical evaluation. 5. Willing and able to provide written informed consent. Exclusion Criteria 1. History of prior sacral Tarlov cyst surgery. 2. Concurrent spinal conditions requiring separate surgical intervention. 3. Active infection or systemic inflammatory disease. 4. Severe comorbidities that increase surgical risk (e.g., advanced cardiac or pulmonary disease). 5. Pregnancy or lactation. 6. Inability to comply with follow-up requirements. 7. Known allergy or contraindication to surgical materials (e.g., fibrin glue).
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT06756984