Network-Based vs. Standardized Cognitive Behavioral Therapy in Chronic Primary Pain
Active, not recruitingNot applicableNCT06784141
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Cognitive-behavioral therapy (CBT) has been shown to be an effective treatment for chronic primary pain (CPP), but overall effect sizes are small to moderate. Process orientation, personalization, and data-driven clinical decision-making may be able to address the heterogeneity among people with CPP and are thus promising ways to increase the effectiveness of CBT for CPP. In a previous study, the feasibility of personalized CBT for CPP using network analysis was investigated. Based on this work, the present study aims to compare this personalized CBT with a standardized CBT as treatment-as-usual condition. In a balanced repeated measures design, a personalized CBT intervention is compared with a standardized CBT intervention. Participants are patients with CPP in German outpatient clinics. Primary and secondary outcome measures (disability, treatment expectations, pain intensity, working alliance, and side effects) will be collected after each study period. In addition, a SCED with randomized baselines will be embedded in the study, in which changes in processes relevant to chronic pain will be evaluated.
Study details
- Official title
- Network-Based vs. Standardized Cognitive Behavioral Therapy in Chronic Primary Pain: A Single-Case Experimental Design With Randomized Baselines
- Conditions
- Chronic Primary Pain
- Interventions
- Behavioral: personalized Cognitive Behavior Therapy including third-wave
- Behavioral: standardized Cognitive Behavior Therapy including third-wave
- Sponsor
- Prof. Dr. Julia Glombiewski
- Organization
- University of Kaiserslautern-Landau
- Start date
- 2025-05-09
- Primary completion
- 2027-04
- Sex
- All
- Age range
- from 18 Years
- Results posted
- No results posted in this snapshot
- Countries
- Germany
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * main diagnosis of chronic pain (i.e. pain persists for at least 6 months and is the most prominent/most burdensome symptom) * subjective impairment/disability (yes-no) * access to a smartphone compatible with the app mPath Exclusion Criteria: * acute hazard due to suicidality, substance abuse, and/or psychosis * only migraine/headache or migraine/headache are the focus of pain * analphabetism * insufficient German knowledge * current psychotherapy * current participation in another intervention study * physical inability to take part in therapy and study sessions
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT06784141