Home-based Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for IBS Pain
RecruitingNot applicableNCT06847360
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The goal of this clinical trial is to learn the feasibility and safety of using home-based taVNS in young adults with IBS to manage their IBS-related pain and symptoms. It will also learn about participants' experience in using the home-based taVNS intervention. The main questions it aims to answer are: * Is it feasible to use a home-based taVNS intervention for pain and symptom management among YAs with IBS? * Is it safe and reported satisfactory to use a home-based taVNS intervention for pain and symptom management among YAs with IBS? Researchers will compare Active to Sham taVNS (a look-alike intervention that contains minimal stimulation) to see if Active taVNS works on managing IBS-related pain and symptoms. Participants will: * Take Active or Sham taVNS intervention for a 6-week treatment (twice daily, 30 minutes per session) * Visit the research lab at the initial setup and the end of the 6-week treatment for checkups and tests * Keep a diary of their symptoms and the number of times they use the taVNS.
Study details
- Official title
- Home-Based Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for Pain and Symptom Management Among Young Adults With Irritable Bowel Syndrome (IBS)
- Conditions
- Pain, Chronic
- Irritable Bowel Syndrome
- Symptom Cluster
- Interventions
- Device: Home-based taVNS intervention
- Sponsor
- Yale University
- Collaborators
- Florida State University; Rutgers University; National Center for Complementary and Integrative Health (NCCIH)
- Start date
- 2026-01-19
- Primary completion
- 2027-09
- Sex
- All
- Age range
- from 18 Years to 29 Years
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * 18 - 29 years of age; * Men and women; * Diagnosis of IBS from a healthcare provider with current report of pain (volunteers asked to bring provider-verification of IBS diagnosis based on Rome IV criteria to initial study appointment); * Experiencing moderate pain (≥3 out of 10 on numeric rating scale \[NRS\]) at least 4 days of the week and lasting previous three months; * Daily access to a computer connected to the internet; and * Able to read and speak English. Exclusion Criteria: * Other chronic pain condition; * Celiac disease or inflammatory bowel disease; * Diabetes mellitus; * severe psychiatric condition requiring inpatient treatment in previous 6 months; * Pregnancy or lactation; * Regular use of opioids or other illicit substances; * use of probiotics or antibiotics within 2 weeks from enrollment; and * any other conditions/contraindications that prohibit the application of taVNS including but not limited to any current or past history of cardiovascular disorders, recent ear trauma, and metal implants above the level of the neck.
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT06847360