Effect of Different Sealers and Activation Methods on Pain
Not yet recruitingPhase 4NCT06860191
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
In this study, the effects of different irrigation agitation methods and different root canal filling sealers on postoperative pain after root canal treatment will be evaluated.
Study details
- Official title
- Evaluation of the Effects of Different Root Canal Sealer and Irrigation Agitation Methods on Postoperative Pain in the Treatment of Teeth with Chronic Apical Periodontitis - Prospective Randomized Clinical Trial
- Conditions
- Chronic Apical Periodontitis
- Interventions
- Drug: Root Canal Sealants
- Sponsor
- TC Erciyes University
- Start date
- 2025-03-01
- Primary completion
- 2025-03-01
- Sex
- All
- Age range
- from 18 Years to 60 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Total sites listed
- 0
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Patients aged 18-60 years who are classified as medically healthy (ASA I or II), * Teeth that do not need periodontal and prosthetic treatment, with a periapical index score between 2 and 4, * Teeth with single root and canal diagnosed with asymptomatic apical periodontitis, * Teeth that respond negatively to electric pulp test (Parkell) or cold test (Endo Ice; Coltene, Altstätten, İsviçre), without pain during percussion and palpation. Exclusion Criteria: * Teeth with PAI scores lower than 2 * Patients who had taken analgesics or anti-inflammatory drugs in the last 4 hours * Diabetic, immunocompromised, pregnant or history of antibiotic use in the last month or patients receiving antibiotic prophylaxis * Teeth with root resorption, immature, severe crown damage, calcified canals, and previous root canal fillings
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT06860191