Spatiotemporal Thalamocortical Alterations Underlie Experimental and Chronic Pain
RecruitingNot applicableNCT06968689
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The purpose of this study is to assess thalamocortical (TC) connectivity during tonic pressure pain, to evaluate alpha activity during tonic pressure pain and to determine pressure pain ratings by using Electroencephalography (EEG), Functional Magnetic Resonance Imaging (fMRI), Transcranial Alternating Current Stimulation (tACS), sham and Transcranial random noise stimulation (tRNS)
Study details
- Official title
- Spatiotemporal Thalamocortical Alterations Underlie Experimental and Chronic Pain - Phase II
- Conditions
- Interventions
- Device: transcranial alternating current stimulation (tACS)
- Device: Sham
- Device: transcranial random noise stimulation (tRNS)
- Sponsor
- The University of Texas Health Science Center, Houston
- Collaborators
- National Institute of Neurological Disorders and Stroke (NINDS)
- Start date
- 2025-06-01
- Primary completion
- 2027-12-31
- Sex
- All
- Age range
- from 18 Years to 60 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Meet the MRI / EEG screening criteria * Fluent in English Exclusion Criteria: * Current or history of major medical, neurological, or psychiatric illness based on self-report * History of cardiac, respiratory, or nervous system disease that, in the investigator's judgment, precludes participation in the study because of a heightened potential for adverse outcome (for example: asthma or claustrophobia) * History of head trauma * Pregnant or lactating * Presence of any contraindications to MRI scanning (for example: cardiac pacemaker, metal implants, claustrophobia, pregnancy, cannot lie still in fMRI scanner) * Conditions making study participation difficult (e.g., paralysis, psychoses, or other severe psychological problems as per the judgment of a study investigator during Session 1) * Active substance abuse disorders (based on subject self-report)
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT06968689