The Effect of Systemic Nonsteroidal Anti-inflammatory Drugs (NSAIDs) Vs Intraoperative Infiltration of Steroids in Tonsillar Bed Following Tonsillectomy on Post Tonsillectomy Pain.
RecruitingNot applicableNCT07035314
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The aim of this study is to compare the efficacy of adding paracetamol to systemic non-steroidal anti-inflammatory drugs (NSAIDs) versus adding dexamethasone as local infiltration to paracetamol on post tonsillectomy pain control.
Study details
- Official title
- The Effect of Systemic Nonsteroidal Anti-inflammatory Drugs (NSAIDs) Vs Intraoperative Infiltration of Steroids in Tonsillar Bed Following Tonsillectomy on Post Tonsillectomy Pain: A Prospective Randomized Controlled Study.
- Conditions
- Tonsillitis Chronic
- Tonsillitis Recurrent
- OSA - Obstructive Sleep Apnea
- Interventions
- Procedure: Dexamethasone
- Drug: NSAIDs
- Drug: Control (Standard treatment)
- Sponsor
- Ain Shams University
- Start date
- 2025-03-08
- Primary completion
- 2025-07-01
- Sex
- All
- Age range
- from 4 Years to 10 Years
- Results posted
- No results posted in this snapshot
- Countries
- Egypt
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Age: Between 4-10 years. * Indications of tonsillectomy such as: * Recurrent acute attacks at least 7 episodes in the past year or at least 5 episodes per year for 2 years or at least 3 episodes per year for 3 years. * Chronic tonsillitis and hypertrophy of tonsils causing sleep apnea, difficulty in deglutition, interference in speech. * Tonsillectomy by cold dissection only. * American Society of Anesthesiologists (ASA) classification 1,2 (Normal Health, Mild systematic disease). Exclusion Criteria: * Patients with age less than 4 and more than 10 years. * Indications of tonsillectomy other than chronic tonsillitis such as lymphoma. * Patients on chronic steroid therapy * Hemoglobin level less than 10 gm/dL * Presence of acute infection in the upper respiratory tract, acute tonsillitis * American Society of Anesthesiologists (ASA) classification ASA 3,4 (Severe systematic disease such as uncontrolled Diabetes, cardiac disease, liver or kidney disease, life threating medical conditions) * Regular use of analgesics within a week of surgery.
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT07035314