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Effectiveness of PRP Pharmacopuncture for Chronic Neck Pain in Cervical Myofascial Syndrome of the Upper Trapezius

RecruitingNot applicableNCT07119255
View the official record on ClinicalTrials.gov

Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.

This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.

Brief summary (from the registry)

The goal of this clinical trial is to learn whether pharmacopuncture with Platelet-Rich Plasma (PRP) is effective for treating chronic neck pain in cervical myofascial syndrome related to the upper trapezius muscle. The main questions it aims to answer are: 1. Is pharmacopuncture with Platelet-Rich Plasma (PRP) effective in reducing chronic neck pain in patients with cervical myofascial syndrome related to the upper trapezius muscle? 2. Does PRP pharmacopuncture improve functional outcomes and quality of life in these patients? 3. Are there any adverse effects associated with PRP pharmacopuncture in this context? Researchers will compare PRP pharmacopuncture to normal saline pharmacopuncture (placebo) to evaluate whether PRP provides greater effectiveness in reducing chronic neck pain in cervical myofascial syndrome related to the upper trapezius muscle. Participants will: * Receive a single session of pharmacopuncture therapy * Undergo evaluations at week 2, week 4, and week 8 after the intervention

Study details

Official title
The Effectiveness of Pharmacopuncture With Platelet-Rich Plasma (PRP) as a Treatment for Chronic Neck Pain in Cervical Myofascial Syndrome Related to the Upper Trapezius Muscle
Interventions
  • Procedure: PRP Pharmacopuncture
  • Procedure: Placebo Pharmacopuncture
Sponsor
Universitas Indonesia
Start date
2025-09-01
Primary completion
2026-08
Sex
All
Age range
from 18 Years to 59 Years
Results posted
No results posted in this snapshot
Countries
Indonesia
Total sites listed
1

Eligibility criteria

Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Male or female, aged 18 to 59 years. * Experiencing neck pain for more than 3 months (chronic). * Neck pain classified as Grade I to III according to the Neck Pain Task Force classification. * Presence of referred pain pattern on physical examination consistent with the distribution of the upper trapezius muscle. * Visual Analogue Scale (VAS) score between 30 and 70 mm (out of 100 mm) during activity (e.g., daily activities or light exercise). * Willing to participate in the study until completion and has signed the informed consent form. Exclusion Criteria: * Hemoglobin level \<13 g/dL for males or \<12 g/dL for females. * Platelet count \<150,000/μL. * Presence of fever (≥37.5°C). * Diagnosis of fibromyalgia. * Structural abnormalities of the cervical spine other than degenerative changes, such as fractures, cervical spine injuries, space-occupying lesions (SOL), infections, neoplasms, or systemic diseases confirmed by radiographic imaging. * History of cervical spine surgery. * Presence of tumors, wounds, or skin infections at the needle insertion site. * Diagnosed with blood disorders or currently taking anticoagulant or antiplatelet medications. * History of hypersensitivity reactions to acupuncture (e.g., metal allergy, severe atopy, keloids, or other skin hypersensitivities). * Uncontrolled cardiovascular disease or diabetes mellitus. * History of pharmacopuncture therapy to the upper trapezius muscle within the past 6 months. * Use of anti-inflammatory medication within the past 2 weeks. * Currently pregnant or breastfeeding.

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT07119255