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Biopsychosocial Factors and Muscle Morphology After a Resistance Exercise

CompletedNot applicableNCT07203430
View the official record on ClinicalTrials.gov

Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.

This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.

Brief summary (from the registry)

The purpose of this study is to evaluate the longitudinal effects of a four-week dynamic resistance training program using the 45-degree Roman chair on pain sensitivity changes after exercise and lumbar muscle performance in individuals with chronic low back pain (LBP). This study will consist of three specific aims. Aim 1 examines changes in local exercise-induced hypoalgesia. Aim 2 will assess changes in lumbar multifidus and erector spinae thickness using ultrasound imaging before and after the intervention. Aim 3 will evaluate changes in lumbar extensor strength (handheld dynamometry (HHD)) and endurance (Biering-Sørensen test).

Study details

Official title
Assessing Adaptations in Biopsychosocial Factors and Muscle Morphology After a Resistance Exercise Intervention in Individuals With Low Back Pain
Interventions
  • Other: 45-Degree Roman Chair Exercise
Sponsor
University of Central Florida
Start date
2025-10-15
Primary completion
2026-04-09
Sex
All
Age range
from 18 Years to 50 Years
Results posted
No results posted in this snapshot
Countries
United States
Total sites listed
1

Eligibility criteria

Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * chronic low back pain lasting ≥ 12 weeks * current pain intensity ≥ 3/10 but no higher than an 8/10 on the Numeric Pain Rating Scale (NPRS) within the past 48 hours * resistance trained (defined as 2x/week for the past 8-12 weeks) * able to read and speak English for informed consent and completion of questionnaires * willing and physically able to complete all testing and intervention sessions. Exclusion Criteria: * History of spinal surgery, fusion, or fracture within the past 6 months * diagnosed degenerative disc disease, scoliosis, or spinal pathology that precludes safe exercise participation * use of an assistive device for walking (cane, walker) within the past year * pregnancy, due to contraindications for exercise testing and ultrasound -body weight ≥ 300 lbs., which exceeds the safe capacity of the Roman chair -- * current tobacco/nicotine use * current enrollment in physical therapy or structured rehabilitation for LBP, * cardiovascular, pulmonary, metabolic, or systemic disease that increases risk during exercise * nociplastic pain conditions (e.g., fibromyalgia) or neurological conditions that confound EIH responses * inability to complete ≥ 8 Roman chair repetitions with proper form during screening * non-English speaking

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT07203430