PRP Spinoplasty for Chronic Low Back Pain With Multiple Pathologies: A Quasi-Experimental Study
CompletedPhase 2NCT07268885
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
This study aimed to evaluate the efficacy and safety of a comprehensive, multi-target injection protocol, termed 'PRP Spinoplasty,' for managing chronic LBP stemming from concurrent lumbar disc and facet joint disease with associated muscle spasms.
Study details
- Official title
- The Efficacy and Safety of Platelet Rich Plasma Spinoplasty in the Management of Lower Back Pain Due to Multiple Pathologies: A Quasi-Experimental Study
- Conditions
- Lower Back Pain Chronic
- Lumbar Disc Disease
- Facet Joint Arthritis
- Interventions
- Biological: Spinoplasty with Platelet Rich Plasma
- Sponsor
- Allmed Medical Center
- Start date
- 2024-09-15
- Primary completion
- 2025-03-01
- Sex
- All
- Age range
- from 18 Years to 80 Years
- Results posted
- No results posted in this snapshot
- Countries
- Palestinian Territories
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Individuals of both sexes; ages between 18 and 80 years. * Lower back pain consistent with lumbosacral radiculopathy, facet arthropathy, and muscle spasms. * MRI-confirmed lumbar spine pathology (disc disease and/or facet arthropathy). * Failure to respond to at least 3 months of conservative therapy (NSAIDS and physical therapy). * Pain score ≥ 6; on the 10-point Numeric Pain Scale (NPS) at baseline. Exclusion Criteria: * Presence of local or systemic infection, or fever. * Diagnosed with cancer within the past 12 months. * Unable to give a consent. * History of spinal deformity such as fracture, or severe spinal stenosis causing neurological deficit. * Presence of lower extremity weakness or urinary tract symptoms related to spinal pathology. * Previous spinal decompression or fusion surgery at the treatment level. * Receipt of any spine injection within the previous 12 months. * Use of NSAIDs within 2 weeks prior to, or 6 weeks following the procedure. * Use of corticosteroids within 6 weeks prior, or after the procedure. * Use of anticoagulation or antiplatelet drugs (excluding low-dose Aspirin). * History of blood disorders. * History of any major surgery within the past 3 months.
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT07268885