Skip to content
Chronic Pain Canada

Psychological Predictors of Pain and Disability in Patients With Chronic Low Back Pain After Manual Therapy

Enrolling by invitationNot applicableNCT07306312
View the official record on ClinicalTrials.gov

Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.

This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.

Brief summary (from the registry)

Low back pain has been reported to cause more disability than any other musculoskeletal health condition worldwide. About eight out of ten people will experience back pain at least once in their lifetime. The parameters that are usually evaluated in a low back pain condition are pain, functional disability and range of motion of the lumbar spine. There are studies that associate psychological conditions (self-efficacy, kinesiophobia, catastrophology, depression, anxiety) with pain and functional disability in patients with low back pain. However, the ability of psychological factors to predict progression after a program of physical therapy or therapeutic methods is not well studied. The main purpose of this study is to investigate the predictive potential of psychological factors in the improvement of pain and functional disability after a manual therapy physiotherapy program in patients with chronic low back pain. A secondary purpose is to investigate the predictive potential of psychological factors in the improvement of pain and functional disability following a program of Pain Neuroscience Education (PNE) in patients with chronic low back pain. In addition, as a secondary purpose, it will be to investigate the effect of combining manual therapy therapy with PNE compared to manual therapy alone in patients with chronic low back pain. This study will involve 60 people aged 18-65 with chronic low back pain, who will be randomly divided by lots into 2 groups of 30 people. The 1st group (30 people) will be treated with manual therapy based on Maitland's principles (interview, evaluation, mobilization), without any use of physiotherapy machines, but with the use of personalized exercises. The 2nd group (30 people) will do the same as group 1 and additional volunteers will participate in before, in a training program in Pain Neuroscience Education (PNE). The total number of sessions that each volunteer will receive will be 6, the duration of each session will be about…

Study details

Official title
Psychological Predictors of Pain and Disability in Patients With Chronic Low Back Pain After Manual Therapy
Conditions
Interventions
Sponsor
University of Thessaly
Start date
2025-12-10
Primary completion
2026-12-31
Sex
All
Age range
from 18 Years to 65 Years
Results posted
No results posted in this snapshot
Countries
Greece
Total sites listed
1

Eligibility criteria

Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Participants should be between 18 and 65 years of age, * the pain in the lumbar region should last for more than 3 months, with at least one attack per week, * they should not have undergone physiotherapy in the last 6 months prior to the intervention * have a good knowledge of the Greek language and an adequate level of knowledge, to be informed and sign the consent form and questionnaires Exclusion Criteria: * people with clinical conditions that are contraindicated for physiotherapy, * patients who report red flags, * people with a history of lumbar surgery, * people with diagnosed neuromuscular diseases that significantly impair movement, * people with cardiovascular and respiratory diseases that cause severe shortness of breath or angina * people with mental disorders, as long as they hinder communication and cooperation with the researcher.

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT07306312