The Impact of Preoperative Chronic Pain on Postoperative Depressive States in Elderly Patients Undergoing Joint Replacement Surgery: A Secondary Analysis Based on Prospective Data
CompletedNCT07403838
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Background: Postoperative depression is a significant complication that hinders recovery in elderly patients undergoing joint replacement surgery. Although preoperative chronic pain is common in this population and pain and depression frequently coexist, the predictive role and underlying mechanisms of preoperative chronic pain on postoperative depression remain unclear. This study aims to systematically explore the association between the two, providing a basis for optimizing perioperative management and improving patient outcomes. Methods: This study is a secondary analysis of multicenter prospective data, including elderly patients who underwent elective knee or hip replacement surgery between April 2020 and April 2022 from a perioperative database of elderly patients in China. The impact of preoperative chronic pain on the occurrence of depressive states within 7 days after surgery was systematically evaluated using univariate and multivariate logistic regression analysis, propensity score matching, and subgroup analysis.
Study details
- Official title
- The Impact of Preoperative Chronic Pain on Postoperative Depressive States in Elderly Patients Undergoing Joint Replacement Surgery: A Secondary Analysis Based on Prospective Data
- Conditions
- Postoperative Depression
- Sponsor
- Chinese PLA General Hospital
- Collaborators
- The Affiliated Hospital Of Guizhou Medical University
- Start date
- 2022-04-30
- Primary completion
- 2024-04-30
- Sex
- All
- Age range
- from 65 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Countries
- China
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: 1. Age ≥ 65 years. 2. No cognitive impairment or history of mental illness. 3. Underwent elective joint replacement surgery. 4. Completed postoperative assessments, including questionnaires for depression, anxiety, and delirium. Exclusion Criteria: 1. Non-general anesthesia. 2. Patients admitted to the intensive care unit postoperatively. 3. Medical centers with fewer than 50 cases. -
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT07403838