Exercise, Insulin Resistance, and Chronic Pain in Postmenopausal Women.
Not yet recruitingNot applicableNCT07407699
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
This study aims to investigate the effects of a combined exercise program on chronic pain in postmenopausal women, considering insulin resistance as a potential physiological mediator. The intervention will assess changes in pain intensity, metabolic and inflammatory biomarkers, psychosocial factors, and body composition. The findings may contribute to understanding the metabolic mechanisms underlying chronic pain in postmenopausal women and support exercise as a non-pharmacological therapeutic strategy.
Study details
- Official title
- Isulin Resistance as a Mediator of Chronic Pain in Postmenopausal Women: Effects of a Combined Exercise Program on Metabolic and Inflammatory Mechanisms
- Conditions
- Chronic Pain
- Postmenopausal
- Insulin Resistance
- Interventions
- Behavioral: Combined Exercise Program
- Other: Usual Care Group
- Sponsor
- São Paulo State University
- Start date
- 2026-08
- Primary completion
- 2027-07
- Sex
- Female
- Results posted
- No results posted in this snapshot
- Total sites listed
- 0
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Postmenopausal women, defined as between 12 months and 5 years since the last menstrual period. * Not using hormone replacement therapy. * Not engaged in regular physical exercise (defined as more than once per week in the last months). * With or without insulin resistance. Exclusion Criteria: * Diagnosis of neurological diseases (e.g., Parkinson's disease, multiple sclerosis, or stroke sequelae). * Severe psychiatric disorders. * Inflammatory autoimmune diseases (e.g., rheumatoid arthritis or systemic lupus erythematosus). * Active neoplasms. * Use of systemic corticosteroids or immunosuppressive drugs within the last three months. * Severe decompensated cardiovascular disease. * Any medical condition that contraindicates participation in physical exercise.
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT07407699