Adding Magnesium Sulphate to Combined Pectointercostal Plane and Erector Spinae Plane Blocks for Acute and Chronic Post-Mastectomy Pain
Not yet recruitingNot applicableNCT07438366
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Given the burden of chronic postmastectomy pain and the need for effective, opioid-sparing analgesia, the propose of the randomized controlled trial is to evaluate the safety and efficacy of adding magnesium sulphate to the combination of PIP block and ESPB in patients undergoing modified radical mastectomy for reducing acute and chronic post mastectomy pain
Study details
- Official title
- Efficacy of Adding Magnesium Sulphate to Combined Pectointercostal Plane Block and Erector Spinae Plane Block for Acute and Chronic Post-Mastectomy Pain After Modified Radical Mastectomy. A Controlled Clinical Trial
- Conditions
- Post-mastectomy Pain Syndrome
- Interventions
- Procedure: Pectointercostal Plane Block (PIPB)
- Procedure: Erector Spinae Plane Block (ESPB)
- Drug: Magnesium sulfate
- Sponsor
- South Egypt Cancer Institute
- Collaborators
- Assiut University
- Start date
- 2026-02-15
- Primary completion
- 2026-11-01
- Sex
- Female
- Age range
- from 18 Years to 65 Years
- Results posted
- No results posted in this snapshot
- Total sites listed
- 0
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Female patients aged ≥18 years. * American Society of Anesthesiologists (ASA) class I-III. * Scheduled for unilateral modified radical mastectomy. Exclusion Criteria: * Known allergy to local anesthetics or magnesium. * Coagulopathy or anticoagulant therapy. * Local infection at injection site. * Body mass index (BMI) ≥ 40 kg/m2. * Chronic opioid use or chronic pain disorders. * Neurological or psychiatric disorders affect pain perception. * Severe hepatic or renal impairment. * Pregnancy. * Lactation.
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT07438366