Post-Amputation Stump Infection as a Predictor of Persistent Residual Limb Pain: A Prospective Cohort Study

Not yet recruitingNCT07438795

View the official record on ClinicalTrials.gov

Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.

This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.

Brief summary (from the registry)

Persistent residual limb pain is common after traumatic amputation and significantly impairs rehabilitation and prosthetic use. Postoperative stump infection may contribute to peripheral nerve sensitization, scar fibrosis, and long-term pain persistence. This prospective cohort study aims to determine whether early post-amputation stump infection independently predicts persistent clinically significant residual limb pain at 3 and 6 months after surgery.

Study details

Official title: Post-Amputation Stump Infection as a Predictor of Persistent Residual Limb Pain: A Prospective Cohort Study
Conditions: Residual Limb Pain
Stump Pain
Post-Amputation Pain
Surgical Site Infection
Phantom Limb Pain (PLP)
Sponsor: Ukrainian Society of Regional Anesthesia and Pain Therapy
Start date: 2026-06-23
Primary completion: 2026-06-23
Sex: All
Age range: from 18 Years to 60 Years
Results posted: No results posted in this snapshot
Total sites listed: 0

Eligibility criteria

Show eligibility criteria (verbatim from the registry)

Inclusion Criteria: * Traumatic upper or lower limb amputation * Enrollment within 4 weeks after surgery * Ability to provide informed consent Exclusion Criteria: * Pre-existing chronic pain in the affected limb * Severe cognitive impairment * Terminal illness limiting follow-up * Refusal or inability to complete follow-up assessments

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT07438795