Comparison of Mesotherapy Treatment Doses in Patients With Chronic Non-Specific Neck Pain

Brief summary (from the registry)

Neck pain is a common health problem in the general population. Approximately 71% of adults experience neck pain at some point in their lives, and its annual prevalence ranges between 30-50% in both the general and working populations. Although neck pain often resolves spontaneously within a few days, it recurs or becomes chronic in about 10% of cases. Mesotherapy was first described in 1958 by Dr. Michel Pistor as a treatment model based on intradermal injections. It involves administering small amounts of active substances into the superficial layers of the skin using specific injection techniques. Mesotherapy typically includes the application of analgesics, local anesthetics, muscle relaxants, and vasodilators. In addition to cosmetic indications, mesotherapy is also used to reduce pain in musculoskeletal conditions. In 2012, the Italian Society of Mesotherapy published a consensus report outlining the indications, contraindications, and scientific evidence regarding the use of mesotherapy in musculoskeletal pain. However, the exact mechanism of action of mesotherapy remains unclear. The present study is designed as a prospective, single-blind, randomized controlled clinical trial to evaluate the effectiveness of mesotherapy in patients with neck pain. Before treatment, volunteers will be randomized into four groups by selecting a card. For each session, the following protocols will be applied: Dry mesotherapy: Needling without injecting any medication. Normal saline group: Mesotherapy with 3 cc of 0.9% NaCl. Full-dose medication mixture: Mesotherapy with lidocaine (local anesthetic), meloxicam (analgesic), and 1 cc of 0.9% NaCl. Half-dose medication mixture: Mesotherapy with half-dose lidocaine, half-dose meloxicam, and 1 cc of 0.9% NaCl. All volunteers will receive one session per week for a total of three weeks. Improvement is expected in all groups, and the aim of the study is to determine which treatment protocol is the most effective in reducing pain and i…

Study details

Official title

Comparison of Mesotherapy Treatment Doses in Patients With Chronic Non-Specific Neck Pain: A Randomised Controlled Double-Blind Clinical Trial

Conditions

• Neck Pain
• Mesotherapy

Interventions

• Drug: Lidocaine %2 ampoule
• Drug: Meloxicam ampoule
• Drug: Saline (0.9% NaCl)
• Other: Dry Needling

Sponsor

Istanbul Medeniyet University

Start date

2025-01-01

Primary completion

2025-06-01

Sex

All

Age range

from 18 Years to 65 Years

Results posted

No results posted in this snapshot

Countries

Turkey (Türkiye)

Total sites listed

1

Eligibility criteria