Feasibility and Effects of Noninvasive Brain Stimulation on Pain Perception in People With Fibromyalgia
Not yet recruitingNot applicableNCT07644221
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The goal of this interventional study is to learn whether noninvasive brain stimulation (NIBS) will have an effect on pain perception in people with fibromyalgia. The main questions it aims to answer are: Do repeated sessions of NIBS lead to a reduction in perceived pain? Do repeated sessions of NIBS lead to an improvement in quality of life? Researchers will compare different brain targets to see if effects are different between them. Participants will receive repeated daily sessions of NIBS over 4 weeks with application of pressure pain algometry, and complete various questionnaires.
Study details
- Official title
- Transcranial Electrical Stimulation for Noninvasive Study of Pain Circuits in Patients With Chronic Pain
- Conditions
- Interventions
- Device: Primary Motor Cortex Stimulation
- Device: Occipital Lobe Stimulation
- Sponsor
- Pulkit Grover
- Collaborators
- Department of Anesthesiology & Perioperative Medicine, University of Pittsburgh; University of Pittsburgh Clinical and Translational Science Institute (CTSI)
- Organization
- Carnegie Mellon University
- Start date
- 2026-06
- Primary completion
- 2027-05
- Sex
- All
- Age range
- from 18 Years to 65 Years
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 2
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Formal diagnosis of fibromyalgia made by a practicing physician * Pain resistant to common analgesics and medications for chronic pain * Existing pain for more than 3 months with an average of at least 4 on a 0 to 10 Numerical Rating Scale (NRS) * Females of child bearing potential must be at least one of the following totally abstinent from heterosexual intercourse since the last menses before start of study, or agree to concurrent use of at least two methods of birth control throughout study participation. Exclusion Criteria: * If the subject is non-ambulatory. * If the subject is female of child-bearing potential, subject must not be pregnant. * Subject must not have a history of brain surgery or uncontrolled neurological conditions, such as seizure, fainting spells, transient ischemic attack. * Subject must not have lifetime history of severe, uncontrolled mood disorders (anxiety, depression, bipolar), psychotic disorders, other neural disorders, or heart disease. * Subject must not have any implanted electronic or metallic devices. * Subject must not have heart diseases, including known arrhythmia, or severe liver or severe gastrointestinal disease or chronic severe infectious disease (e.g. HIV/AIDS).
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT07644221