Light Bulb Stimuli to Reduce Chronic Pain
Not yet recruitingNot applicableNCT07825792
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
This pilot randomized, double-blind, crossover clinical trial will evaluate the feasibility and preliminary efficacy of chromatic (colored) light exposure for reducing pain severity and pain sensitivity in adults with fibromyalgia or chronic widespread pain and fatigue. Participants will complete daily symptom surveys throughout the study and undergo patient-reported outcome assessments and quantitative sensory testing at multiple timepoints. Participants will be randomized to receive either S-cone stimulating chromatic light or equal-energy white light for 2 hours daily over a 7-day treatment period. Following a 1-week washout, participants will cross over to the alternate condition. Outcomes will examine feasibility, changes in pain severity, pain interference, and measures of pain sensitivity. Total study duration is approximately 35 days.
Study details
- Official title
- Chromatic Retinal Stimulation to Reduce Chronic Pain and Pain Sensitivity Using Light Bulbs: A Pilot Randomized Crossover Trial
- Conditions
- Interventions
- Device: S-Cone Stimulating Chromatic Light
- Device: Equal-Energy White Light
- Sponsor
- University of North Carolina, Chapel Hill
- Start date
- 2026-09-21
- Primary completion
- 2028-01-01
- Sex
- All
- Age range
- from 18 Years
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Adults ≥ 18 years of age. * Individuals who have been diagnosed with fibromyalgia or suffer from chronic widespread pain and fatigue. * An average pain severity ≥4 on the 0-10 NRS over the month prior to enrollment. * Pain symptoms present for 3 months or longer. * Pain must be present in 4 out of 5 body regions. * A score of ≥7 on the Widespread pain index (WPI) and ≥5 on the symptom severity scale (SSS), or 4-6 on the WPI and ≥9 on the SSS in the 2016 Fibromyalgia Questionnaire. * Willingness to adjust light levels in home environment so that the illumination (measured in lux) provided by the light bulbs is twice the ambient room illumination (also measured in lux). * Willingness to use study lightbulbs for 2 consecutive hours a day for 7 consecutive days according to study specifications for both conditions (total of 14 days using lightbulbs) * Alert and oriented, and able to provide informed consent * Ability to read and speak English to complete validated questionnaires. Exclusion Criteria: * Vision disorders or conditions resulting in severe vision impairment or blindness * Individuals with self-report of color blindness, uveitis or cataracts. * Prisoner Status * Pregnancy * History of photosensitivity or sensitivity to scintillating (mildly flickering) light. * History of seizure disorder. * Individuals living in households with people who have a history of seizure disorders. * Analgesic treatment plan changes anticipated in the next 3 months (surgery, analgesic medication changes, injections, pain procedures, etc.). * Other history or condition that would, in the investigator's judgment, indicate that the individual would highly likely be non-compliant with the study or unsuitable for the study
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT07825792