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Chronic Neuropathic Pain: clinical trials and information

Neuropathic pain is pain caused by damage to, or disease of, the nervous system. People describe it with words such as burning, shooting, stabbing or electric. It can follow conditions such as diabetes, shingles, nerve injury or chemotherapy.
3
Trials with Canadian sites
2
Recruiting in Canada
23
Registry records worldwide

Chronic Neuropathic Pain clinical trials in Canada

3 trials, recruiting first
PhaseProvinces
Ecstasy to Alleviate SEvere Chronic Neuropathic Pain Trial
NCT07301632
RecruitingPhase 2OntarioUnity Health Toronto2026-01-30
Psilocybin for Enhanced Analgesia in Chronic nEuropathic PAIN
NCT06731335
RecruitingPhase 2OntarioUnity Health Toronto2025-03-05
Methadone in Neuropathic Pain
NCT01205516
TerminatedPhase 4Nova Scotia, Ontario, QuebecNova Scotia Health Authority2013-01

Chronic Neuropathic Pain clinical trials worldwide (outside Canada)

20 trials, 8 recruiting or not yet recruiting. Recruiting first.

PhaseCountries
Hypersound Treatment for Chronic Neuropathic and Radicular Pain
NCT07831447
Not yet recruitingNot applicableUnited StatesHypersound Medical Inc2027-06
aiTBS and rTMS in Neuropathic Pain and Prediction of Response
NCT07650526
RecruitingNot applicableFranceHospital Ambroise Paré Paris2026-09-14
Evaluation of the Efficacy of STNS With FAST and MULTIWAVE in Patients With Refractory Chronic Neuropathic Pain
NCT07154056
RecruitingNot applicableFrancePoitiers University Hospital2026-02-10
Safety and Tolerability Study of ST-503 for Refractory Pain Due to Peripheral Neuropathy (Small Fiber Predominant, SFN)
NCT06980948
RecruitingPhase 1, Phase 2United StatesSangamo Therapeutics2025-12-04
Mechanisms of Stimulation for Pain Alleviation
NCT06741579
RecruitingPhase 3United StatesStanford University2025-09-26
Efficacy of Repetitive Transcranial Magnetic Stimulation Over the Primary Cortex in Patients With Neuropathic Pain and Cancer
NCT07187219
RecruitingNot applicableFranceCentre Hospitalier Universitaire de Saint Etienne2025-06-13
Low Dose Naltrexone for Pain in Patients With HIV
NCT05537935
RecruitingPhase 4United StatesEmory University2023-04-28
Study of RTMS Analgesic Effect in Chronic Neuropathic Pain,
NCT04936646
RecruitingNot applicableFranceUniversity Hospital, Grenoble2021-07-16
Exploring Neurosphere's Remote Monitoring and Virtual Clinic Features in Improve Quality of Life and Reduce Costs
NCT06647576
CompletedUnited StatesMahesh Pattabiraman2024-10-08
Virtual Walking And Transcranial Direct Current Stimulation For Chronic Neuropathic Pain Due To Spinal Cord Injury
NCT06710808
CompletedNot applicableSwitzerlandSwiss Paraplegic Research, Nottwil2024-10-01
High-Frequency rTMS Over the DLPFC for Chronic Low Back Pain
NCT07468799
CompletedNot applicableIndonesiaHasanuddin University2024-01-01
EEG Theta Band Rhythm in SCS
NCT07820657
CompletedNot applicableUnited KingdomWalton Centre NHS Foundation Trust2022-06-16
Transcranial Magnetic Stimulation for Chronic Neuropathic Pain
NCT05593237
Active, not recruitingNot applicableUnited StatesUniversity of California, San Francisco2022-04-25
Surgical Treatment of Chronic Neuropathic Pain
NCT04287075
TerminatedUnited StatesAxogen Corporation2020-02-19
Effectiveness of Repetitive Transcranial Magnetic Stimulation in the Treatment of Chronic Neuropathic Pain
NCT03259451
WithdrawnFranceRennes University Hospital2016-09-26
A Post Market Cohort to Assess the Performance of the Spinal Modulation Neurostimulator System for the Management of Chronic Neuropathic Pain of the Foot and/or Lower Leg
NCT02335489
TerminatedBelgiumAbbott Medical Devices2013-03
Molecular Mediators of Nerve Injury Signaling
NCT01437332
Unknown statusIsraelRambam Health Care Campus2011-09
Study to Evaluate the Efficacy and Safety of ORAVESCENT Fentanyl Citrate for the Management of Breakthrough Pain
NCT00214955
CompletedPhase 3United StatesCephalon2005-09
Effects of Gabapentin in the Treatment of Neuropathic Pain on Driving Performance and Cognition
NCT00189072
TerminatedPhase 4NetherlandsUMC Utrecht2003-04
Effects of Amitriptyline for the Treatment of Pain on Driving Performance and Cognition.
NCT00189059
TerminatedPhase 4NetherlandsUMC Utrecht2002-10

About Chronic Neuropathic Pain

What is Chronic Neuropathic Pain?

Neuropathic pain is pain caused by damage to, or disease of, the nervous system. People describe it with words such as burning, shooting, stabbing or electric. It can follow conditions such as diabetes, shingles, nerve injury or chemotherapy.

How is Chronic Neuropathic Pain usually assessed?

Clinicians usually assess neuropathic pain through a history and a neurological examination, sometimes with questionnaires designed to screen for nerve-related pain, and sometimes with nerve conduction studies or imaging.

What kinds of treatments are studied for Chronic Neuropathic Pain?

Registered studies cover medicines, medical devices (such as nerve stimulators), procedures (such as nerve blocks or injections), physical and movement therapies, psychological approaches (such as cognitive behavioural therapy), education programs and digital tools. Being studied in a trial does not mean a treatment works or is approved. The interventions listed on this page come directly from the registry records.

How can I find Chronic Neuropathic Pain clinical trials in Canada?

This page lists 3 registry records for this term with at least one site in Canada, recruiting studies first. Each trial page links to the official ClinicalTrials.gov record, which lists the study contacts. Recruiting status changes often, so check the registry, and talk to your doctor before joining a study.

Related conditions

Related interventions

Related US FDA drug labels

Labels whose indications text mentions this term. US labels, not Health Canada Product Monographs.

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status.