Drug: Methadone: chronic pain clinical trials
Registry records that list "Drug: Methadone" as an intervention. Being studied does not mean an intervention works or is approved.
1
Trials with Canadian sites
0
Recruiting in Canada
14
Registry records in total
Trials in Canada
1 trial, 0 recruiting or not yet recruiting. Recruiting first.
| Phase | Provinces | ||||
|---|---|---|---|---|---|
| Methadone in Neuropathic Pain NCT01205516 | Terminated | Phase 4 | Nova Scotia, Ontario, Quebec | Nova Scotia Health Authority | 2013-01 |
Trials worldwide (outside Canada)
13 trials, 1 recruiting or not yet recruiting. Recruiting first.
| Phase | Countries | ||||
|---|---|---|---|---|---|
| Methadone to Reduce Chronic Opioid Use After Major Spine Surgery: The MEND Pilot Feasibility Study NCT07222072 | Recruiting | Phase 4 | United States | The Cleveland Clinic | 2025-11-15 |
| Intravenous Methadone in Perioperative Acute and Chronic Management in Chinese Adult Cardiac Surgical Patients NCT05913284 | Active, not recruiting | Phase 3 | Hong Kong | Chinese University of Hong Kong | 2024-01-15 |
| Methadone Anesthesia For Kidney Transplant Receptors NCT04908345 | Unknown status | Phase 3 | Brazil | University of Sao Paulo General Hospital | 2021-05-17 |
| Methadone and Hydromorphone For Spinal Surgery NCT02107339 | Completed | Phase 4 | United States | Endeavor Health | 2014-03 |
| Buprenorphine and Methadone for Opioid-dependent Chronic Back Pain Patients NCT01559454 | Completed | Phase 4 | United States | State University of New York at Buffalo | 2012-02 |
| Methadone and Ketamine for Neuropathic Pain Treatment NCT02233452 | Completed | Phase 4 | Brazil | Universidade Federal de Santa Maria | 2012-01 |
| Development and Evaluation of a Methadone Protocol for Severe Chronic Pain Management NCT02335398 | Completed | Phase 4 | Thailand | Mahidol University | 2011-07 |
| The Effect of Choice of Intraoperative Opioid on Postoperative Pain NCT01542645 | Completed | Phase 4 | United States | Endeavor Health | 2010-09 |
| QTc and Perceived Sleep Follow up Among Chronic Pain Patients With Opiate Medication NCT00999440 | Unknown status | Not applicable | Israel | Tel-Aviv Sourasky Medical Center | 2010-01 |
| Buprenorphine and Methadone for Opioid Dependent Chronic Pain Patients NCT00879996 | Completed | Phase 4 | United States | State University of New York at Buffalo | 2009-04 |
| Opioid Rotation From Morphine to Methadone in Treatment of Non-malignant Pain NCT00356083 | Completed | Phase 3 | Norwegian University of Science and Technology | 2004-01 | |
| Medication Adherence Therapy for Opioid Abusing Pain Patients NCT00249587 | Completed | Phase 1, Phase 2 | United States | National Institute on Drug Abuse (NIDA) | 2000-09 |
| Treatment of Chronic Pain After Spinal Cord Injury (SCI) or Amputation NCT00006448 | Completed | Not applicable | United States | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 1996-08 |
Conditions studied with this intervention
- Pain2 trials
- Chronic Pain2 trials
- Pain, Postoperative2 trials
- Pain, Chronic2 trials
- Spinal Cord Injuries1 trials
- Chronic Disease1 trials
- Chronic Neuropathic Pain1 trials
- Low Back Pain1 trials
- Acute Postoperative Pain1 trials
- Neuropathic Pain1 trials
- Surgery1 trials
- Pain, Acute1 trials
- Anesthesia1 trials
- Post Operative Pain1 trials
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status.