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Sciatica: clinical trials and information

"Sciatica" is the term study registrants used on ClinicalTrials.gov. Registry labels are not always standard medical terms, and close variants of the same label appear as separate entries. In this snapshot the term appears on 18 chronic pain registry records worldwide.
1
Trials with Canadian sites
0
Recruiting in Canada
18
Registry records worldwide

Sciatica clinical trials in Canada

1 trial, recruiting first
PhaseProvinces
Mechanical Diagnosis and Treatment and/or Steroid Injections for Lumbar Radiculopathy
NCT02951377
TerminatedPhase 1AlbertaUniversity of Alberta2017-10-01

Sciatica clinical trials worldwide (outside Canada)

17 trials, 5 recruiting or not yet recruiting. Recruiting first.

PhaseCountries
Hypersound Treatment for Chronic Neuropathic and Radicular Pain
NCT07831447
Not yet recruitingNot applicableUnited StatesHypersound Medical Inc2027-06
Electroacupuncture for Insomnia in Patients With Chronic Sciatica Due to Lumbar Disc Herniation: a Randomized Controlled Trial
NCT07576348
Not yet recruitingNot applicableShanghai Yueyang Integrated Medicine Hospital2026-05
Study to Evaluate Safety of C-1101 Versus Sterile Saline in Adults With Chronic Painful Lumbosacral Radiculopathy
NCT07264270
RecruitingPhase 1AustraliaConsano Bio2025-12-03
A Multicomponent Intervention for Patients With Lumbosacral Radiculopathy: Move-MORE
NCT07125027
RecruitingNot applicableUnited StatesNational University of Natural Medicine2025-08-15
Brain Mechanisms Supporting Cannabis-induced Pain Relief
NCT04982965
RecruitingEarly phase 1United StatesUniversity of California, San Diego2021-05-07
Neurodynamic Moblization Versus Mulligan on Pain and Functional Abilities in Patients With Chronic Discogenic Sciatica
NCT07050108
CompletedNot applicableEgyptCairo University2025-08-10
Effects of Shockwave Therapy Versus Ultrasound Therapy Among Patients With Chronic Sciatica
NCT07710924
CompletedNot applicablePakistanUniversity of Lahore2025-06-30
Non-surgical Spinal Decompression in Patients With Chronic Low Back Pain
NCT06275750
CompletedNot applicableMexicoHospital Civil de Guadalajara2023-08-21
Integrated Supported Biopsychosocial Self-Management for Back Related Leg Pain
NCT05022121
CompletedNot applicableUnited StatesUniversity of Minnesota2022-01-26
Ultrasound-guided Lumbar Periradicular Injection: a Non Irradiating Infiltration Technique
NCT03453775
Unknown statusNot applicableBelgiumUniversité Libre de Bruxelles2018-02-27
Virtual Environment Rehabilitation for Patients With Motor Neglect Trial
NCT03887962
Unknown statusNot applicableUnited KingdomCambridge University Hospitals NHS Foundation Trust2017-05-01
[18F]FTC-146 PET/MRI in Healthy Volunteers and in CRPS and Sciatica
NCT02753101
CompletedEarly phase 1United StatesStanford University2016-02-09
NAPS: Non-awake Versus Awake Placement of Spinal Cord Stimulators
NCT02284542
CompletedUnited StatesSt. Luke's Hospital, Pennsylvania2014-11-01
Neural Dynamics Technique for the Treatment of Chronic Radicular Low Back Pain
NCT01145105
CompletedNot applicableIsraelClalit Health Services2010-06
Total Lumbar Disc Prosthesis and Subsequent Work Activity at at Least Five Years After Total Lumbar Disc Replacement
NCT06989632
CompletedSpainUniversity of Valencia2008-01-01
A Study to Evaluate 90-Day Safety of Tapentadol(CG5503) Immediate Release (IR) or Oxycodone Immediate Release in Patients With Chronic Pain
NCT00364546
CompletedPhase 3Johnson & Johnson Pharmaceutical Research & Development, L.L.C.2006-07
Effect of Antidepressants on Back Pain
NCT00018200
CompletedPhase 2United StatesUS Department of Veterans Affairs1999-04

About Sciatica

What is Sciatica?

"Sciatica" is the term study registrants used on ClinicalTrials.gov. Registry labels are not always standard medical terms, and close variants of the same label appear as separate entries. In this snapshot the term appears on 18 chronic pain registry records worldwide.

How is Sciatica usually assessed?

Assessment of chronic pain generally involves a clinician taking a detailed history, a physical examination and, where relevant, tests to look for underlying causes. Pain rating scales and questionnaires about function, sleep and mood are often used. The approach depends on the person and the condition.

What kinds of treatments are studied for Sciatica?

Registered studies cover medicines, medical devices (such as nerve stimulators), procedures (such as nerve blocks or injections), physical and movement therapies, psychological approaches (such as cognitive behavioural therapy), education programs and digital tools. Being studied in a trial does not mean a treatment works or is approved. The interventions listed on this page come directly from the registry records.

How can I find Sciatica clinical trials in Canada?

This page lists 1 registry record for this term with at least one site in Canada, recruiting studies first. Each trial page links to the official ClinicalTrials.gov record, which lists the study contacts. Recruiting status changes often, so check the registry, and talk to your doctor before joining a study.

Related interventions

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status.