The Glucosamine-study: The Effect of Glucosamine in Treatment of Chronic Low Back Pain
CompletedPhase 4NCT00404079
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Low back pain (LBP) is the most frequent cause of sick leave and disability pension, and degenerative and osteoarthritic (OA) changes is a significant cause of pain and disability. Some indications exist for symptomatic and possible cartilage-structurmodifying effect on knee- and hip-osteoarthritis with glucosamine sulphate (GS). The OA process in the lumbar spine is most likely to OA processes in knees and hips, hence GS could have comparable symptomatic and structural effect on lumbar OA. Study hypothesis: No difference in treatment effect exists between oral intake of GS- or placebo-capsules for patients' with chronic low back pain measured with Roland Morris Disability Questionnaire.
Study details
- Official title
- Phase 4 Study of Glucosamine Sulphate in the Treatment for Chronic Low Back Pain Patients With Degenerative Lumbar MRI Findings
- Conditions
- Interventions
- Drug: Glucosamine sulphate
- Drug: Placebo
- Sponsor
- Ullevaal University Hospital
- Collaborators
- Stiftelsen Helse og Rehabilitering
- Organization
- Oslo University Hospital
- Start date
- 2006-12
- Primary completion
- 2009-08
- Sex
- All
- Age range
- from 25 Years
- Healthy volunteers
- true
- Results posted
- Yes, on ClinicalTrials.gov
- Countries
- Norway
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Low back pain for more than 6 months * Patient older than 25 years old * MRI findings comparable with lumbar degenerative/osteoarthritic changes. Exclusion Criteria: * Spinal stenosis with neurological deficits * Spinal prolapse with neurological deficits * Rheumatoid arthritis, psoriatic arthritis, * Old lumbar fractures * Chronic pain syndromes (e.g. fibromyalgia) * Psychosocial status not suitable for participation * Pregnancy * Breastfeeding * Allergic to shellfish
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT00404079