| Perioperative Vitamin C to Reduce Persistent Pain After Total Knee Arthroplasty NCT06123715 | Recruiting | Phase 2 | Ontario | University Health Network, Toronto | 2024-04-16 |
| A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight and Chronic Low Back Pain NCT07035093 | Active, not recruiting | Phase 3 | | Eli Lilly and Company | 2025-05-29 |
| Effects of LY3848575 Versus Placebo in Participants With Painful Distal Sensory Polyneuropathy NCT06568042 | Completed | Phase 2 | | Eli Lilly and Company | 2024-08-22 |
| A Study to Evaluate Efficacy and Safety of GSK3858279 in Diabetic Peripheral Neuropathic Pain NCT05838755 | Terminated | Phase 2 | British Columbia, Manitoba, Ontario | GlaxoSmithKline | 2023-09-20 |
| Safety and Efficacy of FSD201 for the Treatment of Chronic Pain Associated With Idiopathic MCAS (MCAD) NCT05652907 | Terminated | Phase 2 | Ontario | Quantum Biopharma | 2023-01-19 |
| Evaluating the Efficacy of Intranasal Oxytocin on Chronic Pain NCT04903002 | Active, not recruiting | Phase 2, Phase 3 | Alberta, British Columbia, Newfoundland and Labrador | Memorial University of Newfoundland | 2022-04-01 |
| Reconsolidation Therapy With Propranolol as a Treatment for Chronic Pain NCT05085782 | Completed | Phase 2 | Quebec | Université de Sherbrooke | 2022-02-07 |
| Prevention of Persistent Pain With LidocAine iNfusions in Breast Cancer Surgery (PLAN) NCT04874038 | Active, not recruiting | Phase 3 | Alberta, Newfoundland and Labrador, Nova Scotia, Ontario and 1 more | University Health Network, Toronto | 2021-09-22 |
| Efficacy and Safety of AQX-1125 in Subjects With Chronic Prostatitis/Chronic Pelvic Pain Syndrome NCT03500159 | Terminated | Phase 2 | Ontario | Aquinox Pharmaceuticals (Canada) Inc. | 2018-04-18 |
| Study to Evaluate the Efficacy and Safety of AMG 301 in Migraine Prevention NCT03238781 | Completed | Phase 2 | Alberta, British Columbia, Ontario, Quebec | Amgen | 2017-09-06 |
| Chronic Widespread Pain and White Blood Cell Activation NCT02984397 | Completed | Phase 3 | Quebec | McGill University Health Centre/Research Institute of the McGill University Health Centre | 2016-12 |
| Evaluating the Efficacy of Intranasal Oxytocin Among Individuals With Persistent Pain NCT02888574 | Completed | Phase 2, Phase 3 | Alberta | University of Calgary | 2016-11 |
| Efficacy and Safety of 2 Doses of AQX-1125 in Subjects With Interstitial Cystitis / Bladder Pain Syndrome NCT02858453 | Unknown status | Phase 3 | British Columbia, Ontario, Quebec | Aquinox Pharmaceuticals (Canada) Inc. | 2016-07 |
| A Study to Determine the Efficacy and Safety of Fasinumab for the Treatment of Adults With Chronic Low Back Pain NCT02620020 | Completed | Phase 2, Phase 3 | Ontario | Regeneron Pharmaceuticals | 2016-01-26 |
| Evaluation of Galcanezumab in the Prevention of Chronic Migraine NCT02614261 | Completed | Phase 3 | | Eli Lilly and Company | 2015-11-30 |
| CREATE-1: A Study to Assess the Efficacy and Safety of AXS-02 in Patients With CRPS-1 NCT02504008 | Unknown status | Phase 3 | Quebec | Axsome Therapeutics, Inc. | 2015-07 |
| Randomized Control Trial of the Use of Botox to Treat Chronic Scrotal Pain NCT02249234 | Completed | Phase 2 | Ontario | Mount Sinai Hospital, Canada | 2014-08 |
| Study To Assess Safety, Tolerability And PK Of ATB-346 In Healthy Subjects NCT03220633 | Completed | Phase 1 | Quebec | Antibe Therapeutics Inc. | 2014-06 |
| Long Term Safety of Naldemedine NCT01965652 | Completed | Phase 3 | | Shionogi | 2013-09-24 |
| Effects of Perioperative Pregabalin for Post-Craniotomy Pain NCT01591980 | Withdrawn | Phase 4 | Ontario | Unity Health Toronto | 2013-08 |
| JALYN for Benign Prostatic Hyperplasia (BPH) and Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) NCT01830829 | Terminated | Phase 3 | Ontario | Dr. J. Curtis Nickel | 2013-04 |
| A Study to Characterize the Abuse Liability of ALO-02 in Healthy, Non-Dependent, Recreational Opioid Abusers NCT01746901 | Completed | Phase 1 | Ontario | Pfizer | 2013-02 |
| 16 Week Efficacy and 5 Year Long Term Efficacy, Safety and Tolerability of Secukinumab in Patients With Active Ankylosing Spondylitis NCT01649375 | Completed | Phase 3 | Manitoba, Quebec | Novartis Pharmaceuticals | 2012-10-18 |
| Phase III Trial of Dantonic® (T89) Capsule to Prevent and Treat Stable Angina NCT01659580 | Completed | Phase 3 | British Columbia, Ontario, Quebec | Tasly Pharmaceuticals, Inc. | 2012-08 |
| Ranolazine for Incomplete Vessel Revascularization Post-Percutaneous Coronary Intervention (PCI) NCT01442038 | Completed | Phase 3 | Alberta, New Brunswick, Ontario, Quebec | Gilead Sciences | 2011-10 |
| Efficacy of Perioperative Pregabalin in Reducing the Incidence of Chronic Neuropathic Pain and Postthoracotomy Syndrome. NCT00967135 | Completed | Not applicable | Quebec | Centre hospitalier de l'Université de Montréal (CHUM) | 2010-06 |
| A Safety and Tolerability Study of JNJ-42160443 in Patients With Moderate to Severe, Chronic Knee Pain From Osteoarthritis NCT01094262 | Terminated | Phase 2 | Ontario, Quebec | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | 2010-04-20 |
| A Study to Evaluate the Pain Relieving Effects, Safety, and Tolerability of JNJ-42160443 for the Relief of Bladder Pain NCT01060254 | Terminated | Phase 2 | Ontario | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | 2010-04-06 |
| A Study to Evaluate the Efficacy, Safety, and Tolerability of Tapentadol ER Compared With Placebo in Patients With Chronic, Painful Diabetic Peripheral Neuropathy NCT01041859 | Completed | Phase 3 | Alberta, British Columbia, Ontario, Quebec | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | 2009-12 |
| A Dose-ranging Study of the Safety and Effectiveness of JNJ-42160443 as add-on Treatment in Patients With Osteoarthritis-related Pain NCT00973141 | Terminated | Phase 2 | British Columbia, Newfoundland and Labrador, Ontario, Quebec | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | 2009-09-16 |
| An Efficacy And Safety Study Of Tanezumab For The Treatment Of Pain Associated With Chronic Abacterial Prostatitis NCT00826514 | Completed | Phase 2 | Alberta, British Columbia, Manitoba, Ontario and 1 more | Pfizer | 2009-03-25 |
| Safety and Efficacy Study of Ethosuximide for the Treatment of Complex Regional Pain Syndrome (CRPS) NCT00689585 | Terminated | Phase 2 | Quebec | McGill University Health Centre/Research Institute of the McGill University Health Centre | 2008-09 |
| Pregabalin and Post-thoracotomy Pain NCT00663962 | Completed | Phase 4 | Ontario | Queen's University | 2008-04 |
| Evaluation of Pregabalin in Idiopathic Small Fiber Neuropathy NCT00787462 | Terminated | Not applicable | Alberta | University of Alberta | 2008-02 |
| Surgical Pain After Inguinal Hernia Repair (SPAIHR) NCT00551135 | Completed | Phase 3 | Ontario, Prince Edward Island, Quebec | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | 2008-01 |
| A Study To Evaluate Pregabalin In The Treatment Of Moderate To Severe Chronic Bone Pain Related To Metastatic Cancer NCT00381095 | Terminated | Phase 4 | Ontario | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | 2006-12 |
| Efficacy & Safety Study of Pregabalin to Treat Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) NCT00371033 | Completed | Phase 3 | Ontario | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 2006-03 |
| Trial to Compare Alfuzosin Versus Placebo in the Treatment of Chronic Prostatitis/Chronic Pelvic Pain Syndrome NCT00103402 | Completed | Phase 3 | Ontario | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 2005-02 |
| Efficacy and Safety of SR46349B in Patients With Sleep Disorders in Fibromyalgia NCT00313885 | Completed | Phase 2 | | Sanofi | 2004-04 |