Migraine--Investigational Treatment of Migraine With Noninvasive Brain Stimulation. (tDCS- Migraine)
CompletedNot applicableNCT00521196
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The purpose of this study is to determine whether a painless and noninvasive procedure called Transcranial Direct Current Stimulation (tDCS) can be an effective therapy for the treatment of migraine and migraine-associated pain. Stimulation of the motor cortex with tDCS has already been shown to relieve pain in patients with other chronic pain syndromes, including traumatic spinal cord injury and fibromyalgia. Patients with migraine are usually extremely sensitive to pain. A treatment that targets the areas of the brain that are related to the experience of pain may also help decrease pain in patients with migraine. Pain control with this localized approach may help avoid the problems due to pain medications that affect all organs in the body. We hypothesize that 10 sessions of Transcranial Direct Current Stimulation (tDCS) applied over the area of the brain that controls pain and motor function will decrease pain and headache frequency in patients with migraine.
Study details
- Official title
- Phase 2 Study of the Effect of Transcranial Direct Current Stimulation (tDCS) on Pain and Headache Frequency in Migraine.
- Conditions
- Interventions
- Device: DC Stimulator (Transcranial Direct Current Stimulator)
- Sponsor
- Beth Israel Deaconess Medical Center
- Start date
- 2007-07
- Primary completion
- 2012-01-13
- Sex
- All
- Age range
- from 18 Years to 65 Years
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Subjects must be between 18 and 65 years of age. * The diagnosis must meet the 2004 IHS criteria for migraine without aura, migraine with aura, or chronic migraine. * The duration of the disease must be of at least one year. * Subjects must have maintained their routine preventative medication consistently for at least two months (if applicable) prior to study initiation. Exclusion Criteria: * Patients with major depression with suicidal risk, as clinically defined. * Patients with other known neuropsychiatric disorders. * Patients with other chronic pain disorders * History of substance abuse or dependence within the last six months * Known brain metastasis * History of neurological disorders (such as stroke) * History of brain surgery * Prior experience with tDCS * Abnormal neurological examination, other than those pertaining to the signs of the condition studied in this protocol. * Contraindication to tDCS: metallic hardware in the head or scalp: shrapnel, surgical clips, or fragments from welding
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT00521196