Decapeptyl SR With Livial Add Back Therapy in the Management of Chronic Cyclical Pelvic Pain in Pre Menopausal Women

Inclusion Criteria: * aged between 18 and 45 years inclusive * have a clinical diagnosis of chronic cyclical pelvic pain of at least 6 months duration (with or without evidence of endometriosis) * have had investigations for possible endometriosis within three years prior to screening visit * had regular menstrual cycles (24-42 days) for 3 months prior to screening * treatment with LHRHa is indicated * must be able to understand and be willing to comply with the requirements of the protocol Exclusion Criteria: * treated with any LHRHa within 6 months prior to screening * treated with danazol, gestrinone or cyproterone acetate within 6 months prior to screening * used cyclical progesterones or combined oral contraceptives within one full menstrual cycle prior to screening * treated with any other medication other than analgesics within 3 months prior to screening * continuous or acyclical pelvic pain * known metabolic bone disease * abnormal full blood count or liver or renal function at screening or within 6 months * unexplained vaginal bleeding * bone mineral density age adjusted T Score of -2 or below at screening visit. * any other medical condition or abnormality that would impact on the safety or efficacy of the study treatment * receiving treatment with coumarin or indanedione derivatives * known contraindication or allergy or hypersensitivity to test compounds * pregnancy or lactation * planning a pregnancy within 31 months of screening * of child bearing potential and unwilling to use adequate barrier contraception for the duration of the study * received any investigational drug therapy within 30 days prior to the study * has previously entered the study