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Endometriosis: clinical trials and information

Chronic pelvic pain is pain in the lower abdomen or pelvis that lasts six months or longer. It can be linked to gynecological, urological, gastrointestinal or musculoskeletal conditions, and more than one factor may be involved.
4
Trials with Canadian sites
2
Recruiting in Canada
84
Registry records worldwide

Endometriosis clinical trials in Canada

4 trials, recruiting first
PhaseProvinces
The Effect of Preoperative Pelvic Floor Physical Therapy (Prehabilitation) on Postoperative Pain Following Endometriosis Surgery: A Randomized Controlled Trial
NCT07827794
Not yet recruitingNot applicableAlbertaUniversity of Alberta2027-03-01
Improving Access to Pelvic Health Physiotherapy for Endometriosis
NCT07731776
RecruitingQuebecUniversité de Sherbrooke2026-07-28
Virtual Mindfulness for the Management of Endometriosis Pelvic Pain.
NCT05554497
CompletedNot applicableOntarioUnity Health Toronto2021-02-01
Endometriosis Pelvic Pain Interdisciplinary Cohort Data Registry
NCT02911090
Enrolling by invitationBritish ColumbiaBC Women's Hospital & Health Centre2016-06

Endometriosis clinical trials worldwide (outside Canada)

80 trials, 25 recruiting or not yet recruiting. Recruiting first.

PhaseCountries
Perioperative Yoga Therapy and Endometriosis Surgery
NCT07765680
Not yet recruitingNot applicableFranceUniversity Hospital, Lille2026-10-01
Effects of Physiotherapy on Ultrasound and Clinical Parameters in Women With Dysmenorrhea
NCT07645196
Not yet recruitingNot applicableBelgiumVrije Universiteit Brussel2026-09
Assessing the Mechanisms and Impact of a Novel Cannabinoid Product for Gynecologic Pain
NCT07728695
RecruitingPhase 1, Phase 2United StatesStaci Gruber, Ph.D.2026-09
Cyclobenzaprine for Postoperative Pain in Minimally Invasive Hysterectomy
NCT07664956
Not yet recruitingPhase 4United StatesChristiana Care Health Services2026-07-01
Impact of Pelvic Pain Podcast
NCT07568834
RecruitingNot applicableUnited StatesVanderbilt University Medical Center2026-05-05
Identify a Specific Immune Profile in Patients With Chronic Pelvic Pain Resistant to First-line Treatments by Measuring Th1, Th2, Th17, and Treg Cytokines Produced After Non-specific Functional Cell Stimulation - ImmunoCPP
NCT07429773
RecruitingNot applicableFranceCentre Hospitalier Universitaire de Nice2026-04-14
Whole-Body Cryotherapy as a Non-Pharmacological Treatment to Reduce Chronic Pelvic Pain and Improve Quality of Life in People With Endometriosis
NCT07603960
RecruitingNot applicableUnited KingdomUniversity of Edinburgh2026-04-09
Pelvic Floor Muscle Function and Endometriosis-Related Pelvic Pain
NCT07713108
RecruitingHungaryUniversity of Pecs2026-04-01
Pelvic Floor Physical Therapy and Exercise for Women With Endometriosis and Chronic Pelvic Pain
NCT07733583
RecruitingNot applicableBrazilHospital de Clinicas de Porto Alegre2026-03-05
ActiTENS Mini (Transcutaneous Electrical Stimulation) in Women With Chronic Pain From Pelvic Endometriosis
NCT07317037
Not yet recruitingNot applicableFranceAssistance Publique - Hôpitaux de Paris2026-03-01
Virtual Mindfulness and Endometriosis
NCT07501182
Not yet recruitingNot applicableUnity Health Toronto2026-03
Personalized Exercise Recommendations for Chronic Pelvic Pain Using Reinforcement Learning
NCT07810218
RecruitingNot applicableUnited StatesIcahn School of Medicine at Mount Sinai2026-02-06
Remote Electrical Stimulation as a Long-term Intervention for Endometriosis Flare Ups
NCT06974773
RecruitingNot applicableUnited StatesSamphire Group, Inc.2025-12-04
Study on the Outcomes of Patients Treated in Gynecological Emergency Departments for Pelvic Endometriosis or Suspected Pelvic Endometriosis
NCT07472842
RecruitingNot applicableFranceCentre Hospitalier Intercommunal Creteil2025-10-16
Efficacy of Physical Therapy Treatment in Endometriosis and Its Relationship to Adherence Rates.
NCT06795243
RecruitingNot applicableSpainUniversity of Seville2025-05-01
Impact of Dietary Guidance and Probiotics in the Treatment of Endometriosis and Irritable Bowel Syndrome in Women
NCT07149519
RecruitingNot applicableBrazilUniversity of Sao Paulo2025-03-01
The Sleep-pain Relationship in Women with Endometriosis
NCT06834737
Not yet recruitingNot applicableVrije Universiteit Brussel2025-03
Therapeutic-educational Physiotherapy on Pain, Physical-functionality and Quality of Life in Women With Endometriosis.
NCT06212349
RecruitingNot applicableSpainUniversity of Valencia2024-09-09
Research on the Impact of Chronic Pelvic Pain on Endometriosis
NCT06584760
Not yet recruitingChinaThe Fourth Affiliated Hospital of Zhejiang University School of Medicine2024-09
Esketamine as Treatment for Chronic Pain Due to Endometriosis: a RCT Study
NCT06161805
RecruitingPhase 3NetherlandsReinier de Graaf Groep2024-03-01
Internet-based ACT for Endometriosis and Chronic Pain
NCT06153303
RecruitingNot applicableSwedenSkane University Hospital2024-01-01
Multimodal Physiotherapy Based on Tele-rehabilitation in Chronic Pelvic Pain Associated With Endometriosis
NCT06209346
RecruitingNot applicableSpainUniversity of Alcala2023-11-27
Deep Neural Network Stratification for Use Detecting Endometriosis in Women Affected by Chronic Pelvic Pain (EndoCheck)
NCT05245695
RecruitingUnited StatesAspira Women's Health2022-07-12
Treatment of Chronic Pelvic Pain Due to Endometriosis by Transcutaneous Auricular Vagus Nerve Stimulation
NCT04177511
RecruitingNot applicableFranceHopital Foch2021-12-13
ENDOMET - Novel Diagnostic Tools and Treatments for Endometriosis
NCT01301885
RecruitingFinlandTurku University Hospital2005-10
Ketamine in Central Sensitization
NCT07182032
WithdrawnPhase 4United StatesUniversity Hospitals Cleveland Medical Center2026-02-01
Effect of Tele-Yoga on Pain, Fatigue, and Quality of Life in Endometriosis
NCT07241637
CompletedNot applicableTurkey (Türkiye)Ankara University2025-09-01
Glycemic Regulation as Endometriosis Adjunct Treatment
NCT06611501
Active, not recruitingPhase 2United StatesBoston Children's Hospital2025-05-22
Experiences and Care Pathways Shared on Social Media Regarding 5 Conditions Causing Chronic Pain
NCT07871578
CompletedFranceCentral Hospital, Nancy, France2025-03-17
Impact of Ziwig Endotest® on the Management of Patients With Clinical Symptoms of Endometriosis Inconsistent With Their Imaging Work-up
NCT06794424
Active, not recruitingNot applicableFranceZIWIG2025-03-14
Novel Web-based, Self-directed Intervention for Chronic Pelvic Pain
NCT06352840
CompletedNot applicableUnited StatesUniversity of Michigan2024-06-20
The Living With a Long-Term Condition Study
NCT06072287
Unknown statusUnited KingdomKing's College London2023-06-28
Mindful Movement for Pelvic Pain
NCT05899088
Unknown statusNot applicableThe Miriam Hospital2023-06
Effect of Massage and Hydrotherapy to Improve Well-being and Pain Perception in Endometriosis Patients
NCT06506708
Unknown statusNot applicableSpainUniversidad de Granada2023-05-01
Chronic Pelvic Pain in Endometriosis
NCT05863663
CompletedHungaryUniversity of Pecs2023-01-28
Cannabidiol for the Treatment of Pelvic Pain in Endometriosis (DREAMLAND)
NCT05670353
TerminatedPhase 2, Phase 3BrazilUniversity of Sao Paulo2023-01-03
Therapeutic Exercise and Education in Pain Neurophysiology to Improve Pain Intensity in Women With Endometriosis. Clinical Trial.
NCT05682235
Active, not recruitingNot applicableSpainUniversity of Valladolid2022-12-12
An Investigation of Nomothetic Versus Idiographic Assessment in Chronic Pain
NCT05518630
Unknown statusSwedenUppsala University2022-10-05
Spinal Cord Stimulation for Intractable Chronic Lower Abdominal Neuropathic Pain Caused by Endometriosis
NCT05558540
Unknown statusNot applicableNetherlandsProf. Velja Mijatovic2022-10-01
Relaxin, Matrix Metalloproteinase-2 and Interleukin-6 in Women With Chronic Pelvic Pain
NCT06628479
CompletedTurkey (Türkiye)Sanliurfa Mehmet Akif Inan Education and Research Hospital2022-06-15
Virtual Reality During Ultrasound Examination of Women With Endometriosis
NCT04711408
Unknown statusNot applicableIsraelTel-Aviv Sourasky Medical Center2022-06-14
The Using Postoperative Ketamine and Exploring the Effect on Endometriosis Pain (UPKEEEP) Study
NCT05229653
TerminatedPhase 1United StatesNYU Langone Health2022-04-12
Evaluation of Yoga and Conventional Physical Exercise for Pain and Quality of Life in Women With Endometriosis: A Randomized Clinical Trial
NCT07424859
CompletedNot applicableBrazilBeneficência Portuguesa de São Paulo2022-03-01
Endocare for Pelvic-perineal Pain Related to Endometriosis Used at Home
NCT05172492
Unknown statusNot applicableFranceLucine2021-12-07
Endometriosis and Chronic Endometritis
NCT05824507
CompletedNot applicablePolandJagiellonian University2021-06-01
The Effect of Dienogest vs. Norethindrone Acetate Treatment in Endometriosis
NCT05476172
CompletedNot applicableTurkey (Türkiye)Uludag University2021-04-01
Transcranial Direct Current Stimulation to Reduce Chronic Pelvic Pain in Endometriosis
NCT05231239
Unknown statusPhase 2GermanyCharite University, Berlin, Germany2021-01-01
A Group Therapy Based on the Bio-psycho-social Treatment Approach for Women With Chronic Pelvic and Chronic Belly Pain
NCT04057664
TerminatedSwitzerlandSwiss Paraplegic Research, Nottwil2020-09-01
Evaluation of Nutritional Status, Eating Habits and Improvement of Symptoms With a Nutritional Intervention in Women With enDometriosis
NCT05387161
Unknown statusItalyUniversity of Pavia2020-09-01
A Study of Women Receiving Standard of Care (SOC) for the Treatment of Pelvic Pain Due to Suspected or Confirmed Endometriosis and the Impact on the Disease or Symptom Progression.
NCT04140175
TerminatedUnited StatesAbbVie2020-01-20

About Endometriosis

What is Endometriosis?

Chronic pelvic pain is pain in the lower abdomen or pelvis that lasts six months or longer. It can be linked to gynecological, urological, gastrointestinal or musculoskeletal conditions, and more than one factor may be involved.

How is Endometriosis usually assessed?

Assessment often includes a detailed history, physical and pelvic examination, and tests or imaging chosen to look for specific causes.

What kinds of treatments are studied for Endometriosis?

Registered studies cover medicines, medical devices (such as nerve stimulators), procedures (such as nerve blocks or injections), physical and movement therapies, psychological approaches (such as cognitive behavioural therapy), education programs and digital tools. Being studied in a trial does not mean a treatment works or is approved. The interventions listed on this page come directly from the registry records.

How can I find Endometriosis clinical trials in Canada?

This page lists 4 registry records for this term with at least one site in Canada, recruiting studies first. Each trial page links to the official ClinicalTrials.gov record, which lists the study contacts. Recruiting status changes often, so check the registry, and talk to your doctor before joining a study.

Related interventions

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status.