Chronic Pain Management After Herniorraphy
CompletedPhase 3NCT00772291
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Nowadays, chronic pain mainly as a result of iatrogenic nerve damage is generally considered as the most frequent complication after inguinal hernia surgery. The primary objective of this randomised double-blind placebo-controlled trial is to investigate whether pregabalin reduces pain in patients with chronic pain of neuropathic origin after herniorraphy.
Study details
- Official title
- Chronic Pain Management After Herniorraphy:Pregabalin vs Placebo. A Double-blinded Randomised Controlled Clinical Trial.
- Conditions
- Interventions
- Sponsor
- Erasmus Medical Center
- Start date
- 2007-05
- Primary completion
- 2010-08
- Sex
- All
- Age range
- from 18 Years
- Results posted
- No results posted in this snapshot
- Countries
- Netherlands
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: 1. History of unilateral inguinal herniotomy 2. Establishment of neuropathic character of chronic pain by means the LANSS painscore and DN4 score 3. Abnormal sensitivity (allodynia, dysesthesia, hypoesthesia or dysesthesia) in or around the incisional area 4. Duration pain ≥ 3 months 5. Medial or lateral inguinal hernia 6. Age ≥ 18 years 7. VAS score ≥ 40 mm on Vas scale on which they indicate 'how unpleasant or disturbing the worst pain was that they had today' 8. Grade III or IV pain and discomfort on the 4-point pain and discomfort scale 9. Informed consent (addendum V) Exclusion Criteria: 1. Participation in another trial 2. Age \< 18 years 3. Cognitive disfunction 4. Patient is unable to speak Dutch 5. Hereditary problems of galactose intolerance, Lapp lactase deficiency or glucosegalactose malabsorption 6. Patient classified as American Society of Anaesthesiologist Class 4 7. Renal impairment
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT00772291