Using Functional MRI to Evaluate Cognitive Behavioral Therapy Treatment Response in Adults With Chronic Pain
CompletedPhase 1, Phase 2NCT00796536
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Chronic pain is a condition in which pain continues for 1 month or more beyond the usual recovery period for an injury or illness or persists for months or years due to a chronic condition. A commonly used type of psychotherapy called cognitive behavioral therapy (CBT) has been found to be effective in treating people with chronic pain. The purpose of this study is to determine whether and how CBT geared specifically for treating chronic pain can change the way the brain responds to painful emotional and physical stimuli.
Study details
- Official title
- Using fMRI to Evaluate CBT Treatment Response for Patients With Chronic Pain
- Conditions
- Interventions
- Behavioral: Group cognitive behavioral therapy
- Behavioral: Pain education
- Sponsor
- University of Vermont
- Collaborators
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
- Start date
- 2009-06
- Primary completion
- 2010-06
- Sex
- All
- Age range
- from 18 Years
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * At least 6 months of musculoskeletal non-neuropathic pain confined to lumbar or thoracic back * Meets study threshold for severity of typical pain of 4 or more on a 10-point scale adapted from the McGill Pain Questionnaire * Has ongoing standard pain management from a physician * Agrees to participate in this research study Exclusion Criteria: * Malignancy * Reflex sympathetic dystrophy and/or naturopathic pain * Opioid medication use * Substance use disorder * Neurological disorder, such as epilepsy, stroke, or other medical condition that could confound or interfere with the current study * Major depression or/and dysthymia * Post traumatic stress disorder or panic disorder * Left-handedness * Pregnancy * History of illicit drug use (cocaine, cannabis, heroin) that can result in altered cognition * Exceeding the weight limit on the MRI scanner * Suffering from claustrophobia * Any of the following: cardiac pacemakers, auto defibrillators, neural stimulators, aneurysm clips, metallic prostheses, cochlear implants, any implanted devices (pumps, infusion devices, stents), permanent eye make-up, intrauterine devices, shrapnel injuries
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT00796536