Chronic Post Breast Surgery Pain
TerminatedNot applicableNCT00847067
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The purpose of this study is to learn if paravertebral block (PVB) will reduce chronic pain after surgery. Our hypothesis is that chronic pain from breast surgery as a consequence of central sensitization can be prevented by blocking sensory input to the CNS during surgery and the immediate post-operative period.
Study details
- Official title
- A Prospective, Single-blinded, Randomized, Trial Evaluating the Use of Paravertebral Block to Decrease Chronic Post Breast Surgery Pain.
- Conditions
- Interventions
- Procedure: Paravertebral block
- Procedure: Sham injections
- Sponsor
- Mayo Clinic
- Start date
- 2009-02
- Primary completion
- 2010-04
- Sex
- Female
- Age range
- from 18 Years to 80 Years
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: 1. Female patient who are ≥ 18 and ≤ 80 years of age. 2. Patient with diagnosis of breast cancer. 3. Patient scheduled for modified radical mastectomy or lumpectomy with axillary node dissection 4. Patient scheduled for one of the above listed surgeries with or without sentinel, partial, or complete axillary lymph node dissection 5. Patients scheduled for one of the aforementioned surgeries with or without immediate or delayed reconstruction. Exclusion Criteria: 1. Pre-existing peripheral neuropathy 2. Pre-existing chronic pain 3. Bilateral procedure 4. Previous breast surgery, except biopsy 5. Inability to read, write or speak English. 6. Allergy to amide local anesthetics 7. Contraindications to paravertebral nerve block including, but not limited to severe scoliosis of the spine, skin lesion overlying the block area, abnormal coagulation studies (some of these may not be known until after informed consent is obtained) 8. Pregnancy 9. Emergency surgery 10. Previous recipients of peripheral nerve block. 11. Medical professional whose experience includes caring for patients who have had peripheral nerve blocks.
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT00847067