Reducing Pain and Disability After Breast Cancer Surgery
CompletedNot applicableNCT01089933
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Brief summary (from the registry)
The purpose of this study is to determine if the combination of thoracic paravertebral block and multimodal analgesia will decrease chronic pain and arm morbidity in patients undergoing breast cancer surgery with lymph node dissection as compared to patients receiving local anesthesia with multimodal analgesia.
Study details
- Official title
- Efficacy of Thoracic Paravertebral Block in Reducing Chronic Pain and Disability After Breast Cancer Surgery With Axillary Lymph Node Dissection
- Conditions
- Interventions
- Procedure: Thoracic Paravertebral Block (TPVB)
- Procedure: Local Anesthetic
- Sponsor
- Ottawa Hospital Research Institute
- Collaborators
- Canadian Breast Cancer Foundation
- Start date
- 2009-09
- Primary completion
- 2012-09
- Sex
- Female
- Age range
- from 18 Years
- Results posted
- Yes, on ClinicalTrials.gov
- Countries
- Canada
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Patients with diagnosis of breast cancer * Scheduled for elective modified radical mastectomy, simple mastectomy with SLNB, breast conserving surgery (ie lumpectomy, segmental mastectomy) with ALND or ALND alone (after positive SLNB) Exclusion Criteria: * American Society of Anesthesiologist (ASA) class 4 or 5 * Patients with contraindications to TPVB * Allergy to study medications * Chronic opioid use defined as daily consumption of greater than 20 mg of oral morphine or equivalent for \>7days * Renal insufficiency defined as a creatinine clearance \<40ml/min as calculated using the Cockroft-Gault formula * Preoperative radiation therapy * Inability to achieve normal shoulder range of motion as defined as \<100o of shoulder abduction or flexion
Canadian sites (1)
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT01089933