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Lidocaine 5% Medicated Plaster in Chronic Neuropathic Postoperative Pain

TerminatedPhase 2NCT01155986
View the official record on ClinicalTrials.gov

Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.

This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.

Brief summary (from the registry)

The purpose of this trial is to investigate the efficacy and safety of lidocaine 5% medicated plaster in localized chronic post-operative neuropathic pain in comparison to placebo plaster.

Study details

Official title
Lidocaine 5% Medicated Plaster for the Topical Treatment of Localized Chronic Postoperative Neuropathic Pain.
Interventions
  • Drug: Lidocaine 5% medicated plaster
  • Drug: Placebo topical plaster
Sponsor
Grünenthal GmbH
Start date
2010-08
Primary completion
2012-11
Sex
All
Age range
from 18 Years
Results posted
No results posted in this snapshot
Countries
France
Total sites listed
22

Eligibility criteria

Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Male or female subjects with \>= 18 years of age * Intact skin in the area of topical treatment * Patients suffering from moderate to severe ( 5 or more points on an 11 point Numerical Rating Scale where 10 is the worst possible pain, and 0 indicates no pain) chronic daily postoperative neuropathic pain for the past 6 to 24 months. * Patients should have symptoms for example allodynia (a pain due to a stimulus which does not normally provoke pain); and or dysesthesia (unpleasant, abnormal sense of touch). Exclusion Criteria: * Contraindications to lidocaine 5% medicated plaster, or paracetamol * Evidence or history of alcohol, medication or drug abuse and/or dependency in the past 3 years. * Evidence or history (during the past 3 years) of epilepsy, neurotic personality, psychiatric illness, or suicide risk. * Pregnant or breastfeeding women * Women of childbearing potential who are sexually active without satisfactory contraception for at least 28 days prior to enrollment, during the trial, and until 28 days after the follow-up visit. * Severe renal, hepatic or heart disorder. * Surgery in the past 3 months before screening. * Anticipated need for surgery during the trial, requiring at least regional or general anesthesia. * Pending litigation due to chronic pain or disability. * Participation in another trial of investigational medicinal products or devices parallel to or less than 1 month before entry into the trial, or previous participation in this trial. * Presence of other severe pain that could confound the assessment or self- evaluation of the localized postoperative neuropathic pain. * For patients with chronic postoperative neuropathic pain related to a surgery due to tumors: suspected residual tumor or metastases, chemotherapy or radiotherapy for treatment of tumor(s). * Total anesthesia in the area of localized chronic pain

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT01155986