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Postoperative Pain: clinical trials and information

"Postoperative Pain" is the term study registrants used on ClinicalTrials.gov. Registry labels are not always standard medical terms, and close variants of the same label appear as separate entries. In this snapshot the term appears on 81 chronic pain registry records worldwide.
1
Trials with Canadian sites
1
Recruiting in Canada
81
Registry records worldwide

Postoperative Pain clinical trials in Canada

1 trial, recruiting first
PhaseProvinces
Reducing Opioid Use for Chronic Pain Patients Following Surgery
NCT03675386
RecruitingNot applicableOntarioUniversity Health Network, Toronto2018-10-15

Postoperative Pain clinical trials worldwide (outside Canada)

80 trials, 16 recruiting or not yet recruiting. Recruiting first.

PhaseCountries
Erector Spinae Plane Block for Chronic Pain After Spinal Surgery
NCT07834502
Not yet recruitingNot applicableTurkey (Türkiye)Aydin Adnan Menderes University2026-10-01
Comparison of Two Postoperative Care Strategies After Breast Surgery
NCT07880223
Not yet recruitingNot applicableGreeceMoumtzidou Maria Aikaterini2026-10
Combined Popliteal and Adductor Canal Blocks for Postoperative Analgesia in Children With Cerebral Palsy
NCT07801365
Not yet recruitingNot applicableTurkey (Türkiye)Diskapi Yildirim Beyazit Education and Research Hospital2026-09-14
SPIP vs ESP Block in Cardiac Surgery
NCT07780773
Not yet recruitingNot applicableTurkey (Türkiye)Ondokuz Mayıs University2026-09-10
SPINE-RISK VE: Multimodal Predictive Model for Failed Back Surgery Syndrome in Venezuelan Surgical Patients
NCT07693517
Not yet recruitingVenezuelajuan jose valero quintero,MD2026-09-04
Opioid-Free Anesthesia in FESS: A Prospective ERAS Study
NCT07812389
RecruitingTurkey (Türkiye)Filiz Kaya2026-08-15
FROST-STERN Trial: A Trial of Intraoperative Cryoablation for Post Operative Pain Management After Full Sternotomy
NCT07637370
Not yet recruitingNot applicableUnited StatesRutgers, The State University of New Jersey2026-07-15
SPSIP Block Versus ESP Block for Chronic Pain After Unilateral Breast Surgery
NCT07674836
RecruitingNot applicableTurkey (Türkiye)Engin Çetin2026-07-01
Perioperative Quantitative Sensory Testing and Incision Pain Mapping in Thoracic Surgery
NCT07653932
Not yet recruitingChinaTongji Hospital2026-06-08
Negative Pressure Wound Therapy as a Predictor of Persistent Pain After War-Related Trauma
NCT07475897
Not yet recruitingUkraineCharitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)2026-03-15
Retrolaminar Analgesia for LuMbar Surgery
NCT07334288
RecruitingNot applicableChileUniversidad de los Andes, Chile2026-03-01
Prevention of Chronic Postsurgical Pain in Chronic Opioid Users:
NCT07717151
RecruitingNot applicableFranceCentre Hospitalier Universitaire, Amiens2026-01-14
Study of Lipid Mediators in Chronic Postoperative Pain - LICP
NCT06907810
RecruitingNot applicableBelgiumUniversité Catholique de Louvain2025-03-12
Acute Preoperative Pain and Chronic Post-surgical Pain in Emergency Surgery
NCT06555107
RecruitingNot applicableFranceCentre Hospitalier Universitaire, Amiens2024-08-29
Efficacy and Safety of Liposomal Bupivacaine Injection for Paravertebral Nerve Block in the Treatment of Acute and Chronic Pain After Thoracoscopic Pneumonectomy: A Multicenter, Randomized, Double-blind, Controlled Clinical Trial
NCT06569953
RecruitingPhase 4ChinaThe Second Affiliated Hospital of Chongqing Medical University2024-08-26
Analysis of the Incidence and Risk Factors of Chronic Pain After Cesarean Section
NCT06704490
RecruitingChinaHuazhong University of Science and Technology2024-02-01
Tapentadol vs Tramadol in Arthroscopic Rotator Cuff Repair
NCT07779473
Active, not recruitingGreeceUniversity of Thessaly2026-07-01
Preoperative Pain Neuroscience Education in Patients Undergoing CABG
NCT07783750
CompletedNot applicableTurkey (Türkiye)İsmail Palalı2025-06-23
Effect of Erector Spinae Plane Block on Neuropathic Pain After Abdominal Hysterectomy
NCT07830706
CompletedNot applicableTurkey (Türkiye)Necmettin Erbakan University2025-01-01
The Effect of Intrathecal Morphine and Erector Spina Plan Block on Serum Cytokine Levels and Chronic Pain in Caesarean Section Surgery
NCT06684015
Active, not recruitingTurkey (Türkiye)Ankara University2024-03-01
Efficacy of Parasternal Blocks in Cardiovascular Surgery Patients Undergoing Median Sternotomy
NCT06387095
Unknown statusNot applicableTurkey (Türkiye)Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital2024-02-01
Postoperative Chronic Pain in Gynaecological Cancer Surgery
NCT07077889
CompletedTurkey (Türkiye)Duygu Akyol2024-01-01
Sealers in Chronic Apical Lesions
NCT07339579
CompletedNot applicableTurkey (Türkiye)Kahramanmaras Sutcu Imam University2024-01-01
Thoracic Spinal Versus Thoracic Epidural Anesthesia for Patients with Chronic Obstructive Pulmonary Disease Undergoing Supine Percutaneous Nephrolithotomy for Management of Renal Stones.
NCT06663488
CompletedNot applicableEgyptSohag University2023-08-15
Risk of Failed Epidural in Patients With and Without Chronic Pain and Opioid Use
NCT05662566
CompletedDenmarkEske Kvanner Aasvang2023-03-17
Tapentadol Versus Tramadol Analgesia Post Cardiac Surgery
NCT04718116
Unknown statusNot applicableGreeceAretaieion University Hospital2022-11-01
Incidence of Chronic Pain After Sternotomy
NCT05357963
CompletedTurkey (Türkiye)Ankara City Hospital Bilkent2022-04-20
Incidence of Chronic Pain After Thoracotomy
NCT05177575
Unknown statusTurkey (Türkiye)Atatürk Chest Diseases and Chest Surgery Training and Research Hospital2021-12-16
Incidence of Chronic Pain After Video-Assisted Thoracic Surgery
NCT05187390
Unknown statusTurkey (Türkiye)Atatürk Chest Diseases and Chest Surgery Training and Research Hospital2021-12-14
US-Guided SAPB Versus ESPB on Acute and Chronic Pain After VATS
NCT05160961
Unknown statusNot applicableTurkey (Türkiye)Atatürk Chest Diseases and Chest Surgery Training and Research Hospital2021-12-03
Incidence of Chronic Pain After Thoracic Surgery
NCT05145153
Unknown statusTurkey (Türkiye)Atatürk Chest Diseases and Chest Surgery Training and Research Hospital2021-09-28
The Perioperative Pain Self-Management Program Trial
NCT04979429
CompletedNot applicableUnited StatesVA Office of Research and Development2021-08-03
Using Peripheral Nerve Stimulation (PNS) to Treat Chronic Post-surgical Pain (CPSP) After Knee Surgery
NCT04670042
WithdrawnNot applicableUnited StatesStanford University2021-06-25
BiZact Tonsillectomy in the Pediatric Population
NCT04725305
CompletedNot applicableUnited StatesBaylor College of Medicine2021-06-06
US-Guided ESPB Versus TPVB on Acute and Chronic Pain After VATS
NCT04964401
CompletedNot applicableTurkey (Türkiye)Atatürk Chest Diseases and Chest Surgery Training and Research Hospital2021-04-13
Magnesium Sulfate Infusion on Postoperative Pain in Lumbar Surgery
NCT07418580
CompletedNot applicableTurkey (Türkiye)Sisli Hamidiye Etfal Training and Research Hospital2021-04-01
Duloxetine vs Pregabalin for Thoracotomy Pain
NCT04782310
Unknown statusPhase 4EgyptCairo University2021-03-10
Erector Spine Plane Block Versus Local Infiltration Anaesthesia For Transforaminal Percutaneous Endoscopic Discectomy
NCT05483647
CompletedNot applicableUkraineLviv National Medical University2021-01-01
Bilateral Bi-level Erector Spine Plane Block as a Component of General Anesthesia in Surgical Correction of Spinal Deformations
NCT04697498
Unknown statusNot applicableUkraineLviv National Medical University2020-12-16
Safety, Tolerability, and Pharmacokinetics of HSK21542 in Healthy Volunteers
NCT04110886
CompletedPhase 1AustraliaSichuan Haisco Pharmaceutical Group Co., Ltd2020-07-02
Effect of Intercostal Nerve Block With Ropivacaine Combined With Mecobalamine on Chronic Pain After Thoracic Surgery
NCT04217213
Unknown statusNot applicableChinaXuzhou Medical University2020-01-01
Tonsillectomy Using BiZact™ - a Randomized Side-controlled Clinical Trial
NCT03793816
CompletedNot applicableAustriaMedical University of Vienna2019-09-01
Perioperative Lidocaine Administration in Thoracoscopic Surgery for Improved Postoperative Pain Control
NCT03677817
CompletedPhase 3SwitzerlandUniversity Hospital, Basel, Switzerland2019-04-03
High-Dose Steroid for Knee Arthroplasty Patients Expected to Have Postoperative Pain
NCT03763734
CompletedPhase 4DenmarkCopenhagen University Hospital, Hvidovre2019-01-29
High-Dose Steroid for Hip Arthroplasty Patients Expected to Have Postoperative Pain
NCT03763760
CompletedPhase 4DenmarkCopenhagen University Hospital, Hvidovre2019-01-29
ESP Block, CNP and QoL After VATS
NCT04737902
CompletedColombiaHospital Universitario San Ignacio2019-01-01
Effect of 980nm Diode Laser on Postoperative Pain and Root Canal Disinfection in Endodontic Retreatment Cases
NCT03711357
Unknown statusNot applicableCairo University2018-10
Comparative Analysis of Three Locoregional Anesthesia Methods in Breast Tumour Pathology Surgery
NCT05185752
CompletedNot applicableSpainUniversity of Valencia2018-06-01
Pain After PRP Revascularization and Endodontic Treatment of Non-vital Mandibular Molars With Apical Periodontitis
NCT03350841
Unknown statusNot applicableEgyptCairo University2018-01
QLB and Laparoscopic Nephrectomy, Postoperative Pain and Recovery
NCT03339284
Unknown statusPhase 4FinlandTampere University Hospital2017-12-04

About Postoperative Pain

What is Postoperative Pain?

"Postoperative Pain" is the term study registrants used on ClinicalTrials.gov. Registry labels are not always standard medical terms, and close variants of the same label appear as separate entries. In this snapshot the term appears on 81 chronic pain registry records worldwide.

How is Postoperative Pain usually assessed?

Assessment of chronic pain generally involves a clinician taking a detailed history, a physical examination and, where relevant, tests to look for underlying causes. Pain rating scales and questionnaires about function, sleep and mood are often used. The approach depends on the person and the condition.

What kinds of treatments are studied for Postoperative Pain?

Registered studies cover medicines, medical devices (such as nerve stimulators), procedures (such as nerve blocks or injections), physical and movement therapies, psychological approaches (such as cognitive behavioural therapy), education programs and digital tools. Being studied in a trial does not mean a treatment works or is approved. The interventions listed on this page come directly from the registry records.

How can I find Postoperative Pain clinical trials in Canada?

This page lists 1 registry record for this term with at least one site in Canada, recruiting studies first. Each trial page links to the official ClinicalTrials.gov record, which lists the study contacts. Recruiting status changes often, so check the registry, and talk to your doctor before joining a study.

Related conditions

Related interventions

Related US FDA drug labels

Labels whose indications text mentions this term. US labels, not Health Canada Product Monographs.

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status.