Postoperative Pain: clinical trials and information
Postoperative Pain clinical trials in Canada
| Phase | Provinces | ||||
|---|---|---|---|---|---|
| Reducing Opioid Use for Chronic Pain Patients Following Surgery NCT03675386 | Recruiting | Not applicable | Ontario | University Health Network, Toronto | 2018-10-15 |
Postoperative Pain clinical trials worldwide (outside Canada)
80 trials, 16 recruiting or not yet recruiting. Recruiting first.
| Phase | Countries | ||||
|---|---|---|---|---|---|
| Erector Spinae Plane Block for Chronic Pain After Spinal Surgery NCT07834502 | Not yet recruiting | Not applicable | Turkey (Türkiye) | Aydin Adnan Menderes University | 2026-10-01 |
| Comparison of Two Postoperative Care Strategies After Breast Surgery NCT07880223 | Not yet recruiting | Not applicable | Greece | Moumtzidou Maria Aikaterini | 2026-10 |
| Combined Popliteal and Adductor Canal Blocks for Postoperative Analgesia in Children With Cerebral Palsy NCT07801365 | Not yet recruiting | Not applicable | Turkey (Türkiye) | Diskapi Yildirim Beyazit Education and Research Hospital | 2026-09-14 |
| SPIP vs ESP Block in Cardiac Surgery NCT07780773 | Not yet recruiting | Not applicable | Turkey (Türkiye) | Ondokuz Mayıs University | 2026-09-10 |
| SPINE-RISK VE: Multimodal Predictive Model for Failed Back Surgery Syndrome in Venezuelan Surgical Patients NCT07693517 | Not yet recruiting | Venezuela | juan jose valero quintero,MD | 2026-09-04 | |
| Opioid-Free Anesthesia in FESS: A Prospective ERAS Study NCT07812389 | Recruiting | Turkey (Türkiye) | Filiz Kaya | 2026-08-15 | |
| FROST-STERN Trial: A Trial of Intraoperative Cryoablation for Post Operative Pain Management After Full Sternotomy NCT07637370 | Not yet recruiting | Not applicable | United States | Rutgers, The State University of New Jersey | 2026-07-15 |
| SPSIP Block Versus ESP Block for Chronic Pain After Unilateral Breast Surgery NCT07674836 | Recruiting | Not applicable | Turkey (Türkiye) | Engin Çetin | 2026-07-01 |
| Perioperative Quantitative Sensory Testing and Incision Pain Mapping in Thoracic Surgery NCT07653932 | Not yet recruiting | China | Tongji Hospital | 2026-06-08 | |
| Negative Pressure Wound Therapy as a Predictor of Persistent Pain After War-Related Trauma NCT07475897 | Not yet recruiting | Ukraine | Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans) | 2026-03-15 | |
| Retrolaminar Analgesia for LuMbar Surgery NCT07334288 | Recruiting | Not applicable | Chile | Universidad de los Andes, Chile | 2026-03-01 |
| Prevention of Chronic Postsurgical Pain in Chronic Opioid Users: NCT07717151 | Recruiting | Not applicable | France | Centre Hospitalier Universitaire, Amiens | 2026-01-14 |
| Study of Lipid Mediators in Chronic Postoperative Pain - LICP NCT06907810 | Recruiting | Not applicable | Belgium | Université Catholique de Louvain | 2025-03-12 |
| Acute Preoperative Pain and Chronic Post-surgical Pain in Emergency Surgery NCT06555107 | Recruiting | Not applicable | France | Centre Hospitalier Universitaire, Amiens | 2024-08-29 |
| Efficacy and Safety of Liposomal Bupivacaine Injection for Paravertebral Nerve Block in the Treatment of Acute and Chronic Pain After Thoracoscopic Pneumonectomy: A Multicenter, Randomized, Double-blind, Controlled Clinical Trial NCT06569953 | Recruiting | Phase 4 | China | The Second Affiliated Hospital of Chongqing Medical University | 2024-08-26 |
| Analysis of the Incidence and Risk Factors of Chronic Pain After Cesarean Section NCT06704490 | Recruiting | China | Huazhong University of Science and Technology | 2024-02-01 | |
| Tapentadol vs Tramadol in Arthroscopic Rotator Cuff Repair NCT07779473 | Active, not recruiting | Greece | University of Thessaly | 2026-07-01 | |
| Preoperative Pain Neuroscience Education in Patients Undergoing CABG NCT07783750 | Completed | Not applicable | Turkey (Türkiye) | İsmail Palalı | 2025-06-23 |
| Effect of Erector Spinae Plane Block on Neuropathic Pain After Abdominal Hysterectomy NCT07830706 | Completed | Not applicable | Turkey (Türkiye) | Necmettin Erbakan University | 2025-01-01 |
| The Effect of Intrathecal Morphine and Erector Spina Plan Block on Serum Cytokine Levels and Chronic Pain in Caesarean Section Surgery NCT06684015 | Active, not recruiting | Turkey (Türkiye) | Ankara University | 2024-03-01 | |
| Efficacy of Parasternal Blocks in Cardiovascular Surgery Patients Undergoing Median Sternotomy NCT06387095 | Unknown status | Not applicable | Turkey (Türkiye) | Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital | 2024-02-01 |
| Postoperative Chronic Pain in Gynaecological Cancer Surgery NCT07077889 | Completed | Turkey (Türkiye) | Duygu Akyol | 2024-01-01 | |
| Sealers in Chronic Apical Lesions NCT07339579 | Completed | Not applicable | Turkey (Türkiye) | Kahramanmaras Sutcu Imam University | 2024-01-01 |
| Thoracic Spinal Versus Thoracic Epidural Anesthesia for Patients with Chronic Obstructive Pulmonary Disease Undergoing Supine Percutaneous Nephrolithotomy for Management of Renal Stones. NCT06663488 | Completed | Not applicable | Egypt | Sohag University | 2023-08-15 |
| Risk of Failed Epidural in Patients With and Without Chronic Pain and Opioid Use NCT05662566 | Completed | Denmark | Eske Kvanner Aasvang | 2023-03-17 | |
| Tapentadol Versus Tramadol Analgesia Post Cardiac Surgery NCT04718116 | Unknown status | Not applicable | Greece | Aretaieion University Hospital | 2022-11-01 |
| Incidence of Chronic Pain After Sternotomy NCT05357963 | Completed | Turkey (Türkiye) | Ankara City Hospital Bilkent | 2022-04-20 | |
| Incidence of Chronic Pain After Thoracotomy NCT05177575 | Unknown status | Turkey (Türkiye) | Atatürk Chest Diseases and Chest Surgery Training and Research Hospital | 2021-12-16 | |
| Incidence of Chronic Pain After Video-Assisted Thoracic Surgery NCT05187390 | Unknown status | Turkey (Türkiye) | Atatürk Chest Diseases and Chest Surgery Training and Research Hospital | 2021-12-14 | |
| US-Guided SAPB Versus ESPB on Acute and Chronic Pain After VATS NCT05160961 | Unknown status | Not applicable | Turkey (Türkiye) | Atatürk Chest Diseases and Chest Surgery Training and Research Hospital | 2021-12-03 |
| Incidence of Chronic Pain After Thoracic Surgery NCT05145153 | Unknown status | Turkey (Türkiye) | Atatürk Chest Diseases and Chest Surgery Training and Research Hospital | 2021-09-28 | |
| The Perioperative Pain Self-Management Program Trial NCT04979429 | Completed | Not applicable | United States | VA Office of Research and Development | 2021-08-03 |
| Using Peripheral Nerve Stimulation (PNS) to Treat Chronic Post-surgical Pain (CPSP) After Knee Surgery NCT04670042 | Withdrawn | Not applicable | United States | Stanford University | 2021-06-25 |
| BiZact Tonsillectomy in the Pediatric Population NCT04725305 | Completed | Not applicable | United States | Baylor College of Medicine | 2021-06-06 |
| US-Guided ESPB Versus TPVB on Acute and Chronic Pain After VATS NCT04964401 | Completed | Not applicable | Turkey (Türkiye) | Atatürk Chest Diseases and Chest Surgery Training and Research Hospital | 2021-04-13 |
| Magnesium Sulfate Infusion on Postoperative Pain in Lumbar Surgery NCT07418580 | Completed | Not applicable | Turkey (Türkiye) | Sisli Hamidiye Etfal Training and Research Hospital | 2021-04-01 |
| Duloxetine vs Pregabalin for Thoracotomy Pain NCT04782310 | Unknown status | Phase 4 | Egypt | Cairo University | 2021-03-10 |
| Erector Spine Plane Block Versus Local Infiltration Anaesthesia For Transforaminal Percutaneous Endoscopic Discectomy NCT05483647 | Completed | Not applicable | Ukraine | Lviv National Medical University | 2021-01-01 |
| Bilateral Bi-level Erector Spine Plane Block as a Component of General Anesthesia in Surgical Correction of Spinal Deformations NCT04697498 | Unknown status | Not applicable | Ukraine | Lviv National Medical University | 2020-12-16 |
| Safety, Tolerability, and Pharmacokinetics of HSK21542 in Healthy Volunteers NCT04110886 | Completed | Phase 1 | Australia | Sichuan Haisco Pharmaceutical Group Co., Ltd | 2020-07-02 |
| Effect of Intercostal Nerve Block With Ropivacaine Combined With Mecobalamine on Chronic Pain After Thoracic Surgery NCT04217213 | Unknown status | Not applicable | China | Xuzhou Medical University | 2020-01-01 |
| Tonsillectomy Using BiZact™ - a Randomized Side-controlled Clinical Trial NCT03793816 | Completed | Not applicable | Austria | Medical University of Vienna | 2019-09-01 |
| Perioperative Lidocaine Administration in Thoracoscopic Surgery for Improved Postoperative Pain Control NCT03677817 | Completed | Phase 3 | Switzerland | University Hospital, Basel, Switzerland | 2019-04-03 |
| High-Dose Steroid for Knee Arthroplasty Patients Expected to Have Postoperative Pain NCT03763734 | Completed | Phase 4 | Denmark | Copenhagen University Hospital, Hvidovre | 2019-01-29 |
| High-Dose Steroid for Hip Arthroplasty Patients Expected to Have Postoperative Pain NCT03763760 | Completed | Phase 4 | Denmark | Copenhagen University Hospital, Hvidovre | 2019-01-29 |
| ESP Block, CNP and QoL After VATS NCT04737902 | Completed | Colombia | Hospital Universitario San Ignacio | 2019-01-01 | |
| Effect of 980nm Diode Laser on Postoperative Pain and Root Canal Disinfection in Endodontic Retreatment Cases NCT03711357 | Unknown status | Not applicable | Cairo University | 2018-10 | |
| Comparative Analysis of Three Locoregional Anesthesia Methods in Breast Tumour Pathology Surgery NCT05185752 | Completed | Not applicable | Spain | University of Valencia | 2018-06-01 |
| Pain After PRP Revascularization and Endodontic Treatment of Non-vital Mandibular Molars With Apical Periodontitis NCT03350841 | Unknown status | Not applicable | Egypt | Cairo University | 2018-01 |
| QLB and Laparoscopic Nephrectomy, Postoperative Pain and Recovery NCT03339284 | Unknown status | Phase 4 | Finland | Tampere University Hospital | 2017-12-04 |
About Postoperative Pain
What is Postoperative Pain?
"Postoperative Pain" is the term study registrants used on ClinicalTrials.gov. Registry labels are not always standard medical terms, and close variants of the same label appear as separate entries. In this snapshot the term appears on 81 chronic pain registry records worldwide.
How is Postoperative Pain usually assessed?
Assessment of chronic pain generally involves a clinician taking a detailed history, a physical examination and, where relevant, tests to look for underlying causes. Pain rating scales and questionnaires about function, sleep and mood are often used. The approach depends on the person and the condition.
What kinds of treatments are studied for Postoperative Pain?
Registered studies cover medicines, medical devices (such as nerve stimulators), procedures (such as nerve blocks or injections), physical and movement therapies, psychological approaches (such as cognitive behavioural therapy), education programs and digital tools. Being studied in a trial does not mean a treatment works or is approved. The interventions listed on this page come directly from the registry records.
How can I find Postoperative Pain clinical trials in Canada?
This page lists 1 registry record for this term with at least one site in Canada, recruiting studies first. Each trial page links to the official ClinicalTrials.gov record, which lists the study contacts. Recruiting status changes often, so check the registry, and talk to your doctor before joining a study.
Related conditions
Related interventions
- Drug: placebo (6)
- Drug: Ketamine (3)
- Drug: pregabalin (3)
- Procedure: Erector spinae plane block (3)
- Drug: Saline (2)
- Drug: Bupivacaine (2)
- Drug: lidocaine (2)
- Other: Questionnaire (2)
- Drug: Dexamethasone (2)
- Drug: Tramadol (2)
- Drug: Amitriptyline (1)
- Drug: Ropivacaine (1)
- Other: Acupuncture (1)
- Drug: Diclofenac (1)
- Drug: Sevoflurane (1)
- Device: Ultrasound (1)
- Drug: gabapentin (1)
- Device: tDCS (1)
- Other: placebo (1)
- Drug: duloxetine (1)
Related US FDA drug labels
Labels whose indications text mentions this term. US labels, not Health Canada Product Monographs.
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status.