OASIS: Osteoarthritis Sensitivity Integration Study
WithdrawnNot applicableNCT01377038
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The primary objective of this study is to evaluate the relative efficacy of a centrally-acting analgesic (duloxetine) versus a peripherally acting analgesic (topical diclofenac) for pain and associated symptom management in knee osteoarthritis. Secondary objectives include the determination of which self-report and experimental pain measures best differentiate those who respond better to duloxetine than diclofenac.
Study details
- Official title
- Central Pain Mechanisms in Osteoarthritis: A Longitudinal Cohort
- Conditions
- Interventions
- Other: Phenotype assessment
- Sponsor
- University of Michigan
- Start date
- 2011-09
- Primary completion
- 2015-07
- Sex
- All
- Age range
- from 50 Years
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Diagnosed with knee osteoarthritis as defined by American College of Rheumatology (ACR) criteria * Males and females age greater than 50 years at time of screening Exclusion Criteria: * History of chronic kidney disease or moderate to severe hepatic impairment * History of anemia * Allergy or intolerance of drug intervention * Inability to participate in outcome measures
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT01377038