Acupuncture as an Adjunctive Therapy to the Pharmacological Treatment in Patients With Chronic Pain in Osteoarthritis of the Knee: a Three Armed Randomized Placebo Controlled Trial
CompletedNot applicableNCT01398930
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The objective of this study is to assess the efficacy of acupuncture as an adjunctive therapy to pharmacological treatment of chronic pain due to knee osteoarthritis, as well as for, the improvement of physical functioning, reduction of stiffness, and improvement in quality of life. This is a 3-armed single-blinded randomized sham-controlled trial, comparing acupuncture along with pharmacological treatment, sham acupuncture including pharmacological treatment, and pharmacological treatment alone. One-hundred and twenty patients with knee osteoarthritis were randomly allocated to 3 groups. Group I was treated with etoricoxib, Group II was treated with acupuncture and etoricoxib, and Group III was treated with sham acupuncture and etoricoxib.
Study details
- Conditions
- Interventions
- Sponsor
- National and Kapodistrian University of Athens
- Start date
- 2007-09
- Primary completion
- 2008-07
- Sex
- All
- Age range
- from 35 Years to 75 Years
- Results posted
- No results posted in this snapshot
- Countries
- Greece
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * American College of Rheumatology criteria for diagnosis of knee osteoarthritis * Kellgren-Lawrence (radiologic criterion) score of at least 2 * chronic pain in the knee joint for longer than 3 months Exclusion Criteria: * intra-articular corticosteroid or hyaluronate injection during the last 3 months * corticosteroids * antiplatelet drugs (apart from acetylsalicylic acid 100mg) * immunosuppressive drugs * malignancy of any kind * psychiatric disease * stroke * heart attack * kidney failure * active gastric or duodenal ulcer, or gastrorrhagia * other forms of arthritis * arthroplasty during the last year * previous treatment with acupuncture
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT01398930