Effects of Transcranial Direct Current Stimulation (tDCS) and Transcranial Ultrasound on Osteoarthritis Pain of the Knee
CompletedNot applicableNCT01404052
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The purpose of this study is to see the effects of transcranial direct current stimulation (tDCS) on the pain associated with osteoarthritis of the knee. The investigators hypothesize that there will be a decrease in pain levels with active stimulation, when compared to sham stimulation. Before, during and after stimulation, the investigators will measure and assess changes intracranial blood flow with transcranial ultrasound.
Study details
- Official title
- Effects of Transcranial Direct Current Stimulation and Transcranial Ultrasound on the Perception of Pain Due to Osteoarthritis of the Knee
- Conditions
- Interventions
- Sponsor
- Spaulding Rehabilitation Hospital
- Collaborators
- Highland Instruments, Inc.
- Start date
- 2011-01
- Primary completion
- 2014-07-30
- Sex
- All
- Age range
- from 18 Years to 64 Years
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
STUDY ELIGIBILITY CRITERIA Inclusion Criteria: 1. Providing informed consent to participate in the study 2. 18 to 64 years old 3. Having chronic osteoarthritis knee pain in either knee (existing pain for more than 6 months with an average of at least 3 on a 0-10 VAS scale) 4. Pain resistant to common analgesics and medications for chronic pain such as Tylenol, Aspirin, Ibuprofen, Soma, Parafon Forte DCS, Zanaflex, and Codeine. 5. Must have the ability to feel pain as self reported Exclusion Criteria: 1. Subject is pregnant. 2. Contraindications to tDCS: * metal in the head * implanted brain medical devices 3. Contraindications to TUS: * metal in the head * implanted brain medical devices 4. History of alcohol or drug abuse within the past 6 months as self reported 5. Use of carbamazepine within the past 6 months as self reported. 6. Suffering from severe depression (with a score of \>30 in the Beck Depression Inventory) 7. History of neurological disorders as self reported. 8. History of unexplained fainting spells as self reported, 9. History of head injury resulting in more than a momentary loss of consciousness as self reported 10. History of neurosurgery as self reported
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT01404052