Skip to content

Danhong Injection in the Treatment of Chronic Stable Angina

CompletedPhase 4NCT01681316
View the official record on ClinicalTrials.gov

Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.

This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.

Brief summary (from the registry)

The purpose of this study is to evaluate the effect of Danhong Injection on the relief of angina with the use of the Seattle Angina Questionnaire among patients with stable angina patients

Study details

Official title
A Randomized, Multi-center, Double-blind, Placebo-controlled Trial of Danhong Injection in the Treatment of Chronic Stable Angina
Interventions
Sponsor
China Academy of Chinese Medical Sciences
Collaborators
China Food and Drug Administration
Start date
2012-12
Primary completion
2016-10
Sex
All
Age range
from 18 Years to 70 Years
Results posted
No results posted in this snapshot
Countries
China
Total sites listed
31

Eligibility criteria

Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Female or male inpatients. * Age: 18 - 70 years. * Patients with clinical diagnosis of chronic stable angina and must meet one of the following conditions:1)Patients who have a history of myocardial infarction and ST-T changes;2)Stenosis of more than 50% in at least one major epicardial coronary artery shown by Coronary Angiograph or CT Angiography; 3)Patients with coronary heart disease were determined by radionuclide angiocardiography. * Clinical diagnosis of "Xueyu Zheng" (Blood Stasis Syndrome) as the scores of Chinese medicine symptoms scales of "Xueyu Zheng" in angina ≥ 15. The Chinese medicine symptoms scales of "Xueyu Zheng" is defined as following (1)chest pain-10, (2)chest distress-10, (3) palpitation-5, (4)purple or dark lip-5, (5) purple or dark tongue-5, (6) unsmooth pulse-5. * Patients with moderate angina pectoris (The definition of "moderate angina pectoris " is in accordance with the Canadian Cardiovascular Society (CCS) grading of angina pectoris,which be classified to II or III. * Patient is willing to participate voluntarily and to sign a written patient informed consent. Exclusion Criteria: * Woman with pregnancy, lactation or positive result of pregnancy test, or woman who is under menstrual period. * Woman who disagree with contraception during treatment period * Patients with severe complications that would make the condition more complicated assessed by the investigator, including liver or renal dysfunction, severe cardiopulmonary dysfunction, pulmonary hypertension, chronic obstructive pulmonary disease, a history of epilepsy or cerebral hemorrhage . * Patients who were angina-free during the run-in period without taking any drug. * Patients with myocardial infarction or Canadian Cardiovascular Society (CCS) grading of angina pectoris class IV within the preceding 3 months * Patients with chest pain caused by other disease (e.g., acute myocardial infarction,severe neurosis,menopausal syndrome,hyperthyroidism). * Patients with history of drug-induced bleeding or history of bleeding caused by warfarin. * Patients with history of hematopoietic system diseases. * Patients who had surgery within the past 4 weeks and have hemorrhagic tendency. * Patients who is participating in other trials or has been participated in other trials in recent 3 months. * Patients with history of allergy or suspected allergic to the drug. * Patients who were suspected addicted into alcohol or drug abuse in the past 2 years. * Patients…

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT01681316