Effect of Chemotherapy on Pain Sensitivity and Patient-reported Symptoms
CompletedNCT01983982
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Many breast cancer survivors report chronic pain that develops or worsens following chemotherapy. The impact of chemotherapy on the development of chronic pain is uncertain. In this proposal, we are studying the impact of chemotherapy on a patient's sensitivity to pain. We are also investigating whether a patient's sensitivity to pain is related to how many symptoms she experiences during treatment.
Study details
- Official title
- Effect of Chemotherapy on Pain Sensitivity and Patient-reported Symptoms in Early Stage Breast Cancer
- Conditions
- Sponsor
- University of Michigan
- Collaborators
- Damon Runyon Cancer Research Foundation
- Start date
- 2013-11
- Primary completion
- 2016-01
- Sex
- Female
- Age range
- from 18 Years
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Female gender * Histologically proven stage I-III invasive carcinoma of the breast who is planning to receive a standard dose of adjuvant chemotherapy. * Surgical resection should be complete at the time of study enrollment. * Eastern Cooperative Oncology Group performance status 0-2. Exclusion Criteria: * Average pain over the past 24 hours of 4 or greater on a 0-10 scale. * Peripheral sensory neuropathy grade 2 or higher. * Personal history of schizophrenia or major depressive disorder, or history of suicidal ideation or attempt within the past 2 years. * Thumbnail abnormalities on either hand (such as artificial nails) that are likely to alter pain perception during testing. * Pregnant or nursing. * No prior chemotherapy for any reason
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT01983982