Development and Evaluation of a Methadone Protocol for Severe Chronic Pain Management
CompletedPhase 4NCT02335398
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Methadone is a synthetic mu opioid agonist that has been proved as clinically effective in pain management. However, methadone usage for pain control in Thailand has been limited because physicians are not familiar with its dosing and concern about the risk of drug accumulation and cardiac arrhythmia. Therefore, this prospective study was conducted to evaluate the efficacy and safety of a methadone protocol in Thai patients with severe chronic noncancer and cancer pain.
Study details
- Official title
- Development and Evaluation of a Methadone Protocol for Severe Chronic Pain Management
- Conditions
- Interventions
- Sponsor
- Mahidol University
- Start date
- 2011-07
- Primary completion
- 2013-12
- Sex
- All
- Age range
- from 18 Years
- Results posted
- No results posted in this snapshot
- Countries
- Thailand
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Outpatients aged 18 or over who suffered from severe chronic cancer or noncancer pain to be firstly treated with methadone as analgesics Exclusion Criteria: * QTc interval that was more than 500 msec * History of opioid addiction * Having structural heart diseases * During pregnancy or lactation period * Patients who have hypersensitivity to methadone
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT02335398