Optimizing Chronic Pain Treatment With Enhanced Neuroplastic Responsiveness
CompletedNot applicableNCT02681081
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The purpose of the study is to identify non-invasive strategies that will optimize the neurobiological environment and improve learning and memory in the treatment of chronic pain. The overall aims of the current proposal are to determine if food restriction and/or glucose administration in conjunction with a relaxation/guided imagery exercise will result in neurophysiological changes and functional improvements compared to the relaxation/guided imagery exercise alone.
Study details
- Official title
- Optimizing Chronic Pain Treatment With Enhanced Neuroplastic Responsiveness
- Conditions
- Interventions
- Other: Glucose Administration
- Other: Intermittent Fasting
- Other: Control
- Sponsor
- University of Florida
- Collaborators
- American Pain Society
- Start date
- 2016-02
- Primary completion
- 2019-07-12
- Sex
- All
- Age range
- from 50 Years to 85 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Adults with chronic knee pain with or/at risk of knee osteoarthritis Exclusion Criteria: * Concurrent medical condition that could confound outcome measures or limit the ability to participate completely in the protocol including: neurological conditions (Parkinson's disease, multiple sclerosis, and/or seizures) * History of a head injury or stroke * Diabetes or taking medications to control blood sugar * Mental health issues resulting in hospitalization or outpatient treatment in the past year, and/or psychotropic medication use * Current issue or history of treatment for alcohol or other substance abuse * Cognitive function \< or = 22 on the Mini-Mental Status Exam * Pregnancy * A baseline fasting blood sugar (plasma glucose \> 7mmol/L) or persisting blood pressure \>150/95. * Heart condition such as a prior heart attack, heart surgery (including a stent), frequent chest pain or heart failure * Inability to complete the EEG portion of the study
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT02681081