Does Intraoperative Methadone Prevent Postoperative Pain in Bariatric Surgery?
CompletedPhase 4NCT02775474
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The recent increase in obesity has led to an increase in the need for bariatric surgery. In this group of patients the postoperative pain management is of vital importance. One strategy to improve postoperative analgesia is the use of intraoperative methadone, specially in those patients which regional anesthesia is not feasible. There is evidence that the use of intraoperative methadone can lead to a analgesia lasting 24 to 36 hours, while not associated with increased side effects when compared to other opioids with short or intermediate duration of action. In this study the investigators will evaluate the efficacy of intraoperative methadone in reducing postoperative pain and opioid consumption.
Study details
- Official title
- Does Intraoperative Methadone Prevent Postoperative Pain in Bariatric Surgery?
- Conditions
- Interventions
- Drug: Use of Intraoperative Intravenous Methadone
- Drug: Use of Intraoperative Intravenous Fentanyl
- Sponsor
- University of Sao Paulo General Hospital
- Start date
- 2016-06
- Primary completion
- 2017-01
- Sex
- All
- Age range
- from 18 Years to 65 Years
- Results posted
- No results posted in this snapshot
- Countries
- Brazil
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Open bariatric surgery * No contraindications for any drugs used during the trial * Read, understood and signed the informed consent Exclusion Criteria: * Laparoscopic bariatric surgery * Known allergy to any drugs used during the trial * Cardiovascular disease * Creatinine clearance lower than 60 mL/min/1.73 m2 * Chronic usage of opioids * History of personality disorder
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT02775474