Pain, Postoperative: clinical trials and information
Pain, Postoperative clinical trials in Canada
| Phase | Provinces | ||||
|---|---|---|---|---|---|
| Breaststroke Swimming After Breast Cancer Treatment/Surgery as a Means of Treatment for Seroma, Lymphedema, and Chronic Arm and Chest Pain NCT04080934 | Unknown status | Not applicable | Ontario | Ottawa Hospital Research Institute | 2023-01-01 |
| Prevention of Persistent Pain With LidocAine iNfusions in Breast Cancer Surgery (PLAN) NCT04874038 | Active, not recruiting | Phase 3 | Alberta, Newfoundland and Labrador, Nova Scotia, Ontario, Quebec | University Health Network, Toronto | 2021-09-22 |
| Cognitive Behavioural Therapy to Optimize Post-Operative Recovery Trial NCT04274530 | Completed | Not applicable | Alberta, Newfoundland and Labrador, Ontario | McMaster University | 2021-01-25 |
| Effect of Ketamine on Analgesia Post-Cardiac Surgery NCT02925858 | Completed | Phase 4 | Quebec | Jewish General Hospital | 2017-08-28 |
| Postoperative Analgesia Impact of Narcotic Free Anesthesia NCT01544959 | Completed | Not applicable | Quebec | Université de Sherbrooke | 2010-01 |
| Surgical Pain After Inguinal Hernia Repair (SPAIHR) NCT00551135 | Completed | Phase 3 | Ontario, Prince Edward Island, Quebec | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | 2008-01 |
Pain, Postoperative clinical trials worldwide (outside Canada)
71 trials, 9 recruiting or not yet recruiting. Recruiting first.
| Phase | Countries | ||||
|---|---|---|---|---|---|
| The Efficacy of a Mindfulness-Based Virtual Reality Intervention to Reduce Pain in Postoperative Patients NCT06961695 | Not yet recruiting | Not applicable | Babes-Bolyai University | 2025-05-12 | |
| Cryoablation Effects on Acute and Chronic Pain After Thoracotomy and Thoracoscopy NCT06384664 | Recruiting | Not applicable | United States | University of Michigan | 2024-06-03 |
| Pain Injection Versus Epidural Anesthesia for Hip Surgery in Pediatric Patients With Cerebral Palsy NCT06189781 | Recruiting | Phase 4 | United States | University of California, Los Angeles | 2023-12-01 |
| Pain AND Opioids After Surgery NCT05877157 | Recruiting | Croatia, United Kingdom | University of Aberdeen | 2023-09-25 | |
| Impact of Erector Spinae Plane Block on Chronic Postsurgical Pain in Breast Cancer Patients NCT05494502 | Recruiting | Not applicable | China | Peking University First Hospital | 2023-05-23 |
| Opioid-free Anaesthesia in Breast Cancer Surgery NCT06404983 | Recruiting | Not applicable | Greece | University of Ioannina | 2022-12-28 |
| Prospective Study of Sensation and Satisfaction in Cancer and Transgender Mastectomy Patients NCT06094257 | Recruiting | United States | Weill Medical College of Cornell University | 2022-02-09 | |
| fMRI and IVCM Cornea Microscopy of CXL in Keratoconus NCT04439552 | Recruiting | United States | Boston Children's Hospital | 2021-10-04 | |
| Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain NCT04144972 | Recruiting | Not applicable | United States | University of California, San Francisco | 2019-10-24 |
| Efficacy of Pain Neuroscience Education and Pre-anesthetic Assessment in Reducing Levels of Anxiety, Stress and Pain in Patients Undergoing Elective Total Abdominal Hysterectomy (ENAH Study) NCT05435508 | Completed | Not applicable | Mexico | Instituto Neurociencia Del Dolor | 2024-07-01 |
| Dexmedetomidine for Improved Pain Relief and Recovery in Spine Surgery NCT06685081 | Completed | Not applicable | Egypt | Menoufia University | 2024-07-01 |
| Lumbar ESPB in Hip Replacement Surgery NCT06282666 | Completed | Not applicable | Poland | Medical University of Lublin | 2024-02-19 |
| Effects of IASTM With and Without CT on Pain, ROM, and Functional Disability in Post-Operative Knee Stiffness Patients NCT06551922 | Completed | Not applicable | Pakistan | University of Lahore | 2024-01-28 |
| Intravenous Methadone in Perioperative Acute and Chronic Management in Chinese Adult Cardiac Surgical Patients NCT05913284 | Active, not recruiting | Phase 3 | Hong Kong | Chinese University of Hong Kong | 2024-01-15 |
| Dexmedetomidine and Morphine as Adjuvants to US Guided Erector Spinae Plane Blocks in Elective Thoracic Surgeries NCT05843344 | Unknown status | Not applicable | Greece | Dr Kassiani Theodoraki | 2023-05-01 |
| Prevalence of Pain in the Departments of Surgery and Oncoematology of a Children's Hospital NCT04209764 | Completed | Italy | Giuliano Marchetti | 2022-11-06 | |
| Tapentadol Versus Tramadol Analgesia Post Cardiac Surgery NCT04718116 | Unknown status | Not applicable | Greece | Aretaieion University Hospital | 2022-11-01 |
| Opioid Sparing Anesthesia in Cervical Spine Surgery NCT05717361 | Unknown status | Not applicable | Greece | Evangelismos Hospital | 2022-11-01 |
| The Impact of Esmolol Administration on Postoperative Recovery NCT05567822 | Unknown status | Not applicable | Greece | Aretaieion University Hospital | 2022-10-01 |
| Botulinum Toxin A as Treatment for Chronic Postsurgical Pain Following Lung Cancer Surgery NCT04585620 | Unknown status | Phase 1, Phase 2 | Denmark | Allan Vestergaard Danielsen, MD | 2022-09-01 |
| Epidemiology Study and Risk Factor Analysis on Chronic Post-surgical Pain After Video-assisted Thoracic Surgery NCT05473728 | Completed | China | Peking Union Medical College Hospital | 2022-08-01 | |
| Serratus Anterior Plane Block to Prevent Chronic Postoperative Pain in Breast Cancer NCT05494281 | Unknown status | Not applicable | Morocco | Moroccan Society of Surgery | 2022-08-01 |
| Opioid Sparing Anesthesia in Lumbar Spine Surgery NCT05594407 | Unknown status | Not applicable | Greece | Aretaieion University Hospital | 2022-08-01 |
| The Adolescent Surgery Experience: A Mixed Methods Analysis NCT05482919 | Completed | United States | Children's Hospital of Philadelphia | 2022-06-14 | |
| PENG Block Versus LP Block for THA Postop Pain NCT05261009 | Completed | Phase 4 | United States | Wake Forest University Health Sciences | 2022-06-13 |
| Transcranial Magnetic Stimulation for Chronic Neuropathic Pain NCT05593237 | Active, not recruiting | Not applicable | United States | University of California, San Francisco | 2022-04-25 |
| Opioid-free Anesthesia in Laparoscopic Cholecystectomies NCT05089526 | Unknown status | Not applicable | Greece | Aretaieion University Hospital | 2021-10-11 |
| Naldebain for Pain Management of Laparoscopic Cholecystectomy NCT04808544 | Completed | Phase 2, Phase 3 | Taiwan | E-DA Hospital | 2021-08-30 |
| Naldebain for Pain Control After Bariatric Surgery NCT04651361 | Unknown status | Phase 2, Phase 3 | Taiwan | E-DA Hospital | 2021-06-24 |
| Efficacy of Ultrasound Guided ESP Vs Video-assisted PVB Catheter Placement in Minimally Invasive Thoracic Surgery NCT04729712 | Completed | Not applicable | Ireland | Mater Misericordiae University Hospital | 2021-05-12 |
| Online Mindfulness-based Intervention to Prevent Chronic Pain NCT04848428 | Completed | Not applicable | United States | Florida State University | 2021-05-01 |
| Burst Crossover Trial NCT05372822 | Active, not recruiting | Not applicable | Norway | St. Olavs Hospital | 2021-05-01 |
| The Effect of Both Ultrasound and Fluoroscopy Guide Erector Spinae Plane Blocks NCT05044247 | Unknown status | Not applicable | Taiwan | National Taiwan University Hospital | 2021-04-20 |
| Morphine Versus Ketamine as Adjuvants in Paravertebral Blocks NCT04852484 | Unknown status | Not applicable | Greece | Aretaieion University Hospital | 2021-04-16 |
| Opioid-free Anesthesia With a Mixture of Dexmedetomidine-lidocaine-ketamine NCT04858711 | Unknown status | Not applicable | Greece | Aretaieion University Hospital | 2021-04-01 |
| Lidocaine and Magnesium and Ketamine in Gynecological Surgery NCT04622904 | Unknown status | Not applicable | Greece | Aretaieion University Hospital | 2020-11-14 |
| Transversus Thoracis Muscle Plane Block for Sternotomy Pain in Cardiac Surgery NCT04596163 | Completed | Not applicable | Hong Kong | Chinese University of Hong Kong | 2020-10-15 |
| The Impact of Pecs Blocks on Postmastectomy Pain Syndrome NCT04586751 | Completed | Not applicable | Cyprus, Greece | Aretaieion University Hospital | 2020-08-01 |
| Improved Rehabilitation After Spinal Surgery in Adolescents NCT04183049 | Completed | France | Nantes University Hospital | 2019-12-18 | |
| Peri-operative Use of a Pain Injection in Pediatric Patients With Cerebral Palsy NCT04074265 | Completed | Phase 4 | United States | University of California, Los Angeles | 2019-12-01 |
| Gabapentin and Chronic Post Surgical Pain NCT03867240 | Withdrawn | Phase 3 | United States | Emory University | 2019-06 |
| Chronic Pain and Minor Breast Cancer Surgery NCT03912948 | Completed | France | Institut Claudius Regaud | 2019-04-01 | |
| Persistant Post-mastectomy Pain in Breast Cancer : Incidence and Risk Factors NCT04676438 | Completed | Morocco | Moroccan Society of Surgery | 2018-12-10 | |
| Lidocaine Infusion for Postthoracotomy Pain Syndrome NCT03666299 | Unknown status | Not applicable | China | Guangzhou First People's Hospital | 2018-11-06 |
| Lidocaine Infusion for Pain After Herniotomy NCT03673163 | Unknown status | Not applicable | China | Guangzhou First People's Hospital | 2018-11-06 |
| Paravertebral Versus Pectoralis Block for Post Mastectomy Pain NCT03656679 | Terminated | Not applicable | United States | University of Wisconsin, Madison | 2018-10-18 |
| Spinal Cord Burst Stimulation for Chronic Radicular Pain Following Lumbar Spine Surgery NCT03546738 | Completed | Not applicable | Norway | St. Olavs Hospital | 2018-09-05 |
| Ultrasound-guided Genicular Nerve Block for Total Knee Arthroplasty (GenTKR) NCT04024319 | Completed | Spain | Hospital Clinic of Barcelona | 2018-05-28 | |
| Hyperalgesia, Persistent Pain, and Fentanyl Dosing in On-Pump Coronary Artery Bypass Grafting NCT03450161 | Completed | Phase 4 | Belgium | University Hospital, Ghent | 2018-05-14 |
| QLB After Nephrectomy NCT03529201 | Completed | Not applicable | Poland | Medical University of Lublin | 2018-05-07 |
About Pain, Postoperative
What is Pain, Postoperative?
"Pain, Postoperative" is the term study registrants used on ClinicalTrials.gov. Registry labels are not always standard medical terms, and close variants of the same label appear as separate entries. In this snapshot the term appears on 77 chronic pain registry records worldwide.
How is Pain, Postoperative usually assessed?
Assessment of chronic pain generally involves a clinician taking a detailed history, a physical examination and, where relevant, tests to look for underlying causes. Pain rating scales and questionnaires about function, sleep and mood are often used. The approach depends on the person and the condition.
What kinds of treatments are studied for Pain, Postoperative?
Registered studies cover medicines, medical devices (such as nerve stimulators), procedures (such as nerve blocks or injections), physical and movement therapies, psychological approaches (such as cognitive behavioural therapy), education programs and digital tools. Being studied in a trial does not mean a treatment works or is approved. The interventions listed on this page come directly from the registry records.
How can I find Pain, Postoperative clinical trials in Canada?
This page lists 6 registry records for this term with at least one site in Canada, recruiting studies first. Each trial page links to the official ClinicalTrials.gov record, which lists the study contacts. Recruiting status changes often, so check the registry, and talk to your doctor before joining a study.
Related conditions
Related interventions
- Drug: Fentanyl (5)
- Drug: Dexmedetomidine (5)
- Drug: normal saline (4)
- Drug: pregabalin (3)
- Drug: placebo (2)
- Drug: Ropivacaine (2)
- Drug: Methadone (2)
- Drug: Ketamine (2)
- Drug: Bupivacaine (2)
- Drug: lidocaine (2)
- Procedure: Erector spinae plane block (2)
- Drug: Ropivacaine injection (2)
- Drug: Placebo solution (2)
- Drug: Remifentanil (2)
- Drug: Ketamine Hydrochloride (1)
- Drug: Paracetamol (1)
- Drug: Oxycodone (1)
- Drug: Sevoflurane (1)
- Drug: gabapentin (1)
- Other: placebo (1)
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status.