Paravertebral Morphine Versus Dexmedetomidine on Acute and Chronic Postmastectomy Pain
Unknown statusPhase 1, Phase 2NCT02935933
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Evaluate the effect of addition of morphine, dexmedetomidine to bupivacaine in PVB could improve the analgesic effect and thus reduce postoperative morphine consumption and development of chronic neuropathic pain, compared to PVB with bupivacaine , in patients undergoing major breast cancer surgery, i.e., modified radical mastectomy (MRM) and breast conservation surgery with axillary lymph node dissection.
Study details
- Official title
- Safety and Efficacy of Paravertebral Morphine Versus Dexmedetomidine on Acute and Chronic Pain
- Conditions
- Interventions
- Drug: bupivicaine
- Drug: morphine
- Drug: Dexmedetomidine
- Sponsor
- Assiut University
- Start date
- 2016-10
- Primary completion
- 2017-09
- Sex
- Female
- Age range
- from 25 Years to 70 Years
- Results posted
- No results posted in this snapshot
- Countries
- Egypt
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * physical status classes I to III ( weight 50 - 85 kg), will be scheduled for unilateral modified radical mastectomy (MRM) with axillary evacuation will be consecutively enrolled. Exclusion Criteria: * patient refusal, * patients with a known allergy to investigated drugs, * bleeding disorders, * anatomical abnormalities, * infection in the paravertebral region, * pregnancy, breast feeding, * a history of drug or alcohol abuse, and patients with chronic pain or regularly receiving analgesics. * patients subjected for bilateral mastectomy or any unilateral breast surgery other than MRM with axillary evacuation.
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT02935933