Acute Pain: clinical trials and information
Acute Pain clinical trials in Canada
| Phase | Provinces | ||||
|---|---|---|---|---|---|
| Pecto-Intercostal Fascial Plane Block Catheter Trial for Reduction of Sternal Pain NCT05054179 | Unknown status | Phase 2, Phase 3 | British Columbia | University of British Columbia | 2022-09-07 |
| Intra-operative Lidocaine Infusion in Preventing CPSP Post VATs NCT02862769 | Unknown status | Phase 4 | Ontario | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 2017-01-01 |
| A Clinical Study in Healthy Adults Who Sometimes Take Drugs for Pleasure to Investigate the Safety and Tolerability of GRT0151Y and to Find Out Which Single Dose of the Compound is Maximally Tolerated NCT03765658 | Completed | Phase 1 | Ontario | Grünenthal GmbH | 2006-01-20 |
Acute Pain clinical trials worldwide (outside Canada)
63 trials, 9 recruiting or not yet recruiting. Recruiting first.
| Phase | Countries | ||||
|---|---|---|---|---|---|
| Building a Swiss Pain Registry: A National Framework for Acute and Chronic Pain Assessment NCT07717762 | Not yet recruiting | Switzerland | Insel Gruppe AG, University Hospital Bern | 2026-07-15 | |
| Dose-Response Effects of a Brief Audio-Guided Mindfulness Intervention for Acute Pain NCT07562412 | Recruiting | Not applicable | United States | Florida State University | 2026-04-29 |
| Multimodal Imaging and Biospecimen Collection for Low Back Pain (LBPB) NCT06967363 | Not yet recruiting | China | Peking University Third Hospital | 2025-05-15 | |
| Acute Preoperative Pain and Chronic Post-surgical Pain in Emergency Surgery NCT06555107 | Recruiting | Not applicable | France | Centre Hospitalier Universitaire, Amiens | 2024-08-29 |
| Efficacy and Safety of Liposomal Bupivacaine Injection for Paravertebral Nerve Block in the Treatment of Acute and Chronic Pain After Thoracoscopic Pneumonectomy: A Multicenter, Randomized, Double-blind, Controlled Clinical Trial NCT06569953 | Recruiting | Phase 4 | China | The Second Affiliated Hospital of Chongqing Medical University | 2024-08-26 |
| Brief Mindfulness Intervention for Pain Before an In-clinic Orthopedic Procedure NCT06471075 | Recruiting | Not applicable | United States | Florida State University | 2024-08-22 |
| Understanding the Acute Pain Phenotype in Patients Undergoing Surgery NCT06466941 | Recruiting | United States | Brigham and Women's Hospital | 2024-07-03 | |
| Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA NCT05754190 | Recruiting | United States | Brown University | 2023-06-20 | |
| Evaluating the Impact of Focused Muscle Contraction Therapy in U.S. Veterans NCT05094297 | Recruiting | Not applicable | United States | University of Illinois at Chicago | 2021-10-01 |
| Does Patient Testimonial Improve the Pain Relief Derived From a Brief Intervention NCT07335159 | Completed | Not applicable | United States | Florida State University | 2026-01-05 |
| Development of Atılım Kinesiophobia Scale NCT06278012 | Unknown status | Turkey (Türkiye) | Atılım University | 2024-01-01 | |
| Adding Ketamine to Levobupivacaine in Paravertebral Block in Thoracotomy NCT06011746 | Completed | Phase 4 | Egypt | Tanta University | 2023-08-30 |
| Defining a PK and PD Model for Peripheral Analgesia After IV Oxytocin NCT05929339 | Completed | Phase 2 | United States | Wake Forest University Health Sciences | 2023-08-17 |
| Acute and Chronic Pain After One-stage Hybrid Arrhythmia Ablation Surgery NCT05211492 | Terminated | Not applicable | Belgium | Universitair Ziekenhuis Brussel | 2023-02-01 |
| IVs With Buzzy in Chronic Pain Patients NCT05555173 | Withdrawn | Not applicable | United States | Steward St. Elizabeth's Medical Center of Boston, Inc. | 2022-10-01 |
| Comparison of the Effects of TFPB and Anterior QLB on Postoperative Analgesia in Cesarean Section Surgery NCT05408403 | Completed | Not applicable | Turkey (Türkiye) | Ondokuz Mayıs University | 2022-06-18 |
| Comparison Erect Spine in Cardiac Surgery NCT04313959 | Unknown status | Phase 3 | Brazil | Instituto do Coracao | 2022-01-20 |
| Erector Spinae Plane Block in Uniportal VATS NCT04892901 | Completed | Italy | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 2022-01-01 | |
| Effects of Mirror Therapy Versus Fine Motor Activities on Hand Function in Chronic Stroke Patients. NCT05506826 | Completed | Not applicable | Pakistan | Riphah International University | 2022-01-01 |
| US-Guided SAPB Versus ESPB on Acute and Chronic Pain After VATS NCT05160961 | Unknown status | Not applicable | Turkey (Türkiye) | Atatürk Chest Diseases and Chest Surgery Training and Research Hospital | 2021-12-03 |
| Effects of Multimodal Analgesia on Serum MCP-1, BDNF, and MiRNA-124 in Hysterectomy Surgery NCT05069311 | Completed | Not applicable | Indonesia | Udayana University | 2021-10-15 |
| Comparison of Erector Spinae Plane Block and Pectoral Nerve Block for Acute and Chronic Pain in Mastectomies NCT05069805 | Unknown status | Not applicable | Brazil | Hospital de Base | 2021-10-01 |
| US-Guided Serratus Anterior Plane Block Versus Thoracic Epidural in Patients Undergoing Thoracotomy NCT05672394 | Completed | Not applicable | Egypt | National Cancer Institute, Egypt | 2021-06-01 |
| The Use of Venlafaxine in Reducing Pain in Primary Total Knee Replacement NCT05023278 | Completed | Phase 4 | United States | University of California, San Francisco | 2021-05-10 |
| US-Guided ESPB Versus TPVB on Acute and Chronic Pain After VATS NCT04964401 | Completed | Not applicable | Turkey (Türkiye) | Atatürk Chest Diseases and Chest Surgery Training and Research Hospital | 2021-04-13 |
| A Depression and Opioid Pragmatic Trial in Pharmacogenetics (DCRI Coordinating Center) NCT04445792 | Completed | Not applicable | United States | Duke University | 2021-02-24 |
| Pilot Study on the Effects of Low-Level Laser Therapy Treatment for Acute and Persistent Discomfort NCT04774783 | Unknown status | Not applicable | United States | Arkansas Colleges of Health Education | 2021-02-22 |
| Erector Spine Plane Block Versus Local Infiltration Anaesthesia For Transforaminal Percutaneous Endoscopic Discectomy NCT05483647 | Completed | Not applicable | Ukraine | Lviv National Medical University | 2021-01-01 |
| Bilateral Bi-level Erector Spine Plane Block as a Component of General Anesthesia in Surgical Correction of Spinal Deformations NCT04697498 | Unknown status | Not applicable | Ukraine | Lviv National Medical University | 2020-12-16 |
| Comparison of the Effects of QLB 2 and QLB 3 on Post-operative Analgesia in Cesarean Section Surgery NCT04364906 | Completed | Not applicable | Turkey (Türkiye) | Ondokuz Mayıs University | 2020-04-29 |
| Double-blind, Placebo-control, Study to Evaluate the Safety and Pharmacokinetics of CT-044 HCl, in Healthy Volunteers NCT04175743 | Unknown status | Phase 1 | United States | Lotus Clinical Research, LLC | 2019-12-04 |
| Evaluating the Impact of Focused Muscle Contraction Therapy in Retire APF Players NCT04822311 | Completed | Not applicable | United States | University of Illinois at Chicago | 2019-10-24 |
| Pectoral Nerve Block II and Erector Spine Plane Block in Breast Cancer Surgery NCT04135157 | Completed | Not applicable | Turkey (Türkiye) | Ondokuz Mayıs University | 2019-07-01 |
| Virtual Reality Experiences on Acute Pain and Distress NCT03599479 | Completed | Not applicable | South Korea | Seoul National University | 2018-12-27 |
| The Role of Cognitive Function and Electroencephalography on Acute and Chronic Pain After Surgery NCT03761576 | Unknown status | China | Yi Feng, MD | 2018-12-21 | |
| Spinal Manipulation and Patient Self-Management for Preventing Acute to Chronic Back Pain NCT03581123 | Completed | Phase 3 | United States | University of Minnesota | 2018-11-01 |
| Virtual Reality for Pain Management in Advanced Heart Failure NCT04572425 | Completed | Not applicable | United States | Medstar Health Research Institute | 2018-10-01 |
| Medical Mindfulness: Virtual Reality Mindfulness Therapy for Anxiety and Pain Management in Patients With Acute and Chronic Pain NCT04534101 | Suspended | United States | Stanford University | 2018-07-10 | |
| Acute and Persistent Pain in ICU Patients NCT03432546 | Completed | Finland | Tampere University Hospital | 2018-04-06 | |
| The Influence of Different Anesthesia on Acute and Chronic Postsurgical Pain After Thoracic Surgery NCT03847363 | Unknown status | China | Shanghai Zhongshan Hospital | 2018-04-01 | |
| Evaluation And Risk Assessment For Persistent Postsurgical Pain After Breast Surgery NCT03408717 | Active, not recruiting | Singapore, United States | KK Women's and Children's Hospital | 2018-01-03 | |
| Postoperative Peripheral Nerve Stimulation for Management of Post-amputation Pain NCT03484429 | Completed | Not applicable | United States | Hunter Holmes Mcguire Veteran Affairs Medical Center | 2017-12-01 |
| Efficacy Transverse Abdominal Plane (TAP) Block Renal Transplant Surgery NCT03181438 | Unknown status | Not applicable | Brazil | Federal University of São Paulo | 2017-06-03 |
| Ketamine's Effect Changes the Cortical Electrophysiological Activity Related to Semantic Affective Dimension of Pain NCT03915938 | Completed | Phase 2, Phase 3 | Hospital de Clinicas de Porto Alegre | 2017-01-02 | |
| Tactile Acuity in Experimentally Induced Acute Low Back Pain NCT03021278 | Completed | Not applicable | Poland | The Jerzy Kukuczka Academy of Physical Education in Katowice | 2017-01 |
| Paravertebral Morphine Versus Dexmedetomidine on Acute and Chronic Postmastectomy Pain NCT02935933 | Unknown status | Phase 1, Phase 2 | Egypt | Assiut University | 2016-10 |
| TEAS-induced Analgesia: Dual vs Single Acupoints NCT02543580 | Completed | Not applicable | China | Xijing Hospital | 2015-07 |
| Pain Predict Genetics NCT02383342 | Active, not recruiting | Netherlands | Radboud University Medical Center | 2015-05-12 | |
| The Effects of TAP Block on Postsurgical Pain After Minimally Invasive Partial Nephrectomy: NCT02460640 | Completed | Not applicable | Italy | Regina Elena Cancer Institute | 2015-05 |
| Ketamine as Adjunctive Analgesic With Bupivacaine in Paravertebral Analgesia for Breast Cancer Surgery NCT02462681 | Completed | Phase 1, Phase 2 | Egypt | Assiut University | 2015-05 |
About Acute Pain
What is Acute Pain?
"Acute Pain" is the term study registrants used on ClinicalTrials.gov. Registry labels are not always standard medical terms, and close variants of the same label appear as separate entries. In this snapshot the term appears on 66 chronic pain registry records worldwide.
How is Acute Pain usually assessed?
Assessment of chronic pain generally involves a clinician taking a detailed history, a physical examination and, where relevant, tests to look for underlying causes. Pain rating scales and questionnaires about function, sleep and mood are often used. The approach depends on the person and the condition.
What kinds of treatments are studied for Acute Pain?
Registered studies cover medicines, medical devices (such as nerve stimulators), procedures (such as nerve blocks or injections), physical and movement therapies, psychological approaches (such as cognitive behavioural therapy), education programs and digital tools. Being studied in a trial does not mean a treatment works or is approved. The interventions listed on this page come directly from the registry records.
How can I find Acute Pain clinical trials in Canada?
This page lists 3 registry records for this term with at least one site in Canada, recruiting studies first. Each trial page links to the official ClinicalTrials.gov record, which lists the study contacts. Recruiting status changes often, so check the registry, and talk to your doctor before joining a study.
Related interventions
- Drug: PF-04457845, FAAH inhibitor (6)
- Drug: oxycodone hydrochloride (4)
- Drug: morphine (3)
- Procedure: nerve block (3)
- Drug: Ketamine (3)
- Drug: placebo (3)
- Drug: Saline (2)
- Other: Questionnaire (2)
- Procedure: acupuncture (1)
- Procedure: Placebo (1)
- Drug: Dexamethasone (1)
- Other: placebo (1)
- Drug: Ropivacaine (1)
- Drug: Propofol (1)
- Drug: Sevoflurane (1)
- Drug: Remifentanil (1)
- Drug: lidocaine (1)
- Drug: Dexmedetomidine (1)
- Other: Questionnaires (1)
- Drug: Matching Placebo (1)
Related US FDA drug labels
Labels whose indications text mentions this term. US labels, not Health Canada Product Monographs.
- Morphine Sulfate Tablets
- Fentanyl transdermal system
- Morphine Sulfate Oral Solution 2 mg/mL and 4 mg/mL
- Fentanyl transdermal system
- Fentanyl transdermal system
- Fentanyl transdermal system
- Morphine Sulfate Tablets
- FDA drug label 22055b20
- Fentanyl transdermal system
- Fentanyl transdermal system
- Morphine Sulfate Tablets
- Morphine Sulfate Tablets
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status.