Ketamine and Magnesium in Post-operative Pain Control in Patients Treated With Opioids
TerminatedPhase 1NCT02940509
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The goal of this research proposal is to determine if the intraoperative administrative of Ketamine and Magnesium during laparoscopic gynecologic surgery improves postoperative pain in patients on chronic opioid therapy for management of chronic pelvic pain.
Study details
- Official title
- The Role of Ketamine and Magnesium in Post-operative Pain Control After Laparoscopic Surgery in Patients With Chronic Pelvic Pain Treated With Opioids: A Double-Blinded Randomized Control Trial.
- Conditions
- Interventions
- Drug: Ketamine plus Magnesium sulfate
- Drug: Placebo
- Sponsor
- Milton S. Hershey Medical Center
- Start date
- 2017-07-01
- Primary completion
- 2018-02-27
- Sex
- Female
- Age range
- from 18 Years to 80 Years
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: 1. Subjects undergoing elective laparoscopic gynecologic surgery 2. Patients with chronic pelvic pain defined as pain that has persisted for more than 6 months in duration which is localized to the pelvis, anterior abdominal wall, lower back or buttocks and has leads to functional disability or medical care1 3. Patients requiring opioids daily for \>1 month 4. Consenting adults age 18-80 5. American Society of Anesthesiologists (ASA) Physical Status classification II to ASA III Exclusion Criteria: 1. Patient refusal 2. Chronic Kidney disease (Creatinine\>2) 3. Patients treated with methadone 4. Known allergy or adverse effect of ketamine or magnesium 5. Patient unable to give informed consent 6. Patient with limited or no English fluency 7. Uncontrolled hypertension
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT02940509