Human Brain Adaptation to Chronic Pain and Its Effects on Opioid Use
TerminatedNCT03248765
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The purpose of this study is to determine if the research results obtained in animal models of pain - that show that being in pain for some time increases opioid use beyond what is expected to treat the current pain - also apply to patients with chronic pain.
Study details
- Official title
- Human Brain Adaptation to Chronic Pain and Its Effects on Opioid Use
- Conditions
- Interventions
- Other: post-surgical opioid use measured at 1 day and 1 week.
- Sponsor
- Washington University School of Medicine
- Start date
- 2017-08-30
- Primary completion
- 2020-09-11
- Sex
- All
- Age range
- from 18 Years to 65 Years
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: 1. Age 18-65 2. With and without history of chronic muscle-skeletal pain \* 3. Scheduled to undergo elective abdominal surgery requiring overnight hospital admission 4. Opioid naïve\*\* 5. Willing to comply with study procedures as outlined in the protocol 6. Willing and able to provide informed consent 7. Having an email address and access to a computer or electronic tablet Exclusion Criteria: 1. Current use of opioids (includes ANY use in past 3 months) 2. Cancer diagnosis 3. Patient presenting the following documented conditions: Untreated psychosis Current suicidal ideation Current substance abuse
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT03248765