QLB and Radical Cystectomy, Postoperative Pain

Brief summary (from the registry)

There are ca 1000 new cases of bladder cancer in Finland/year. The curative therapy for high risk bladder cancer is radical cystectomy. The golden standard is still an open surgery despite development of laparoscopic techniques. Epidural analgesia is considered as most effective for the treatment of postoperative pain. However, there is a need for other effective options, because epidural analgesia has some contraindications and risks for serious complications. Recently quadratus lumborum block has gained popularity in the treatment of postoperative pain after various surgeries in the area from hip to mamilla. It is more beneficial than other peripheral blocks, since it covers also the visceral nerves. Contrary to the need of epidural catether a single shot QLB has reported to last up to 48 hours. Inadequately treated acute postoperative pain is considered as one of the main risk factors for persistent postoperative pain. 44 patients aging 18-85 will be recruited based on a power calculation. The primary outcome measure is the acute postoperative need for rescue analgesics. Secondary outcomes are acute pain (NRS scale), nausea, vomiting, mobilisation and longterm outcomes such as quality of life and persistent pain.

Study details

Official title

Comparing Two Different Analgesic Block Methods for Postoperative Pain and Recovery After Surgery -Quadratus Lumborum Block (QLB): the Effect on Peri- and Postoperative Pain and Recovery After Radical Cystectomy

Conditions

• Postoperative Pain
• Chronic Pain Post-Proceduraal
• Nausea and Vomiting, Postoperative

Interventions

• Procedure: QLB

Sponsor

Tampere University Hospital

Start date

2017-04-27

Primary completion

2020-08-31

Sex

All

Age range

from 18 Years to 85 Years

Results posted

No results posted in this snapshot

Countries

Finland

Total sites listed

1

Eligibility criteria