Effect of Buglossoides Oil on Recent Chronic Non-injurious Hip and Knee Pain

Inclusion Criteria: 1. Men or non-pregnant women, using an effective form of birth control (such as oral contraceptives, injectable contraceptives or the barrier method such as a intrauterine device (IUD) with a spermicide, a diaphragm with a spermicide, a condom with a spermicide or a sponge with a spermicide) for at least 3 months prior to entry into the study and continuing during participation in the study. 2. 18 to 65 years of age, inclusive. 3. Body mass index (BMI) 18 - 39.9 kg/m2 4. Subject has recent (less than 6 months) current chronic (having lasted more than two weeks) knee (one or both) and/or hip pain that is not the result of an acute injury. Pain intensity is 20 mm or higher using a Visual Analog Scale ranging from 0-100 mm. 5. Subject has no planned knee or hip surgery. 6. Subject is willing to avoid alcohol consumption for 24h prior to every clinic visit. 7. The subject will not modify smoking habits during supplementation period. 8. No significant medical conditions that in the opinion of the qualified physician, would preclude the subject's participation in the study. 9. Signed informed consent. 10. Willing to follow all study procedures including study visits, fasting blood draws, stable body weight, normal eating habits, current activity level, and compliance with study preparation. 11. Willing to not consume fish, crustaceans and shellfish for the duration of the study. 12. Willing to avoid taking anti-inflammatory medications (analgesics and NSAIDs) for 24 hours prior to Visits 2 and 5. Exclusion Criteria: 1. Pregnancy or lactation. Women trying to conceive. Women who will try to conceive who are unwilling to commit to the use of a medically approved form of contraception throughout the study period. Method of contraception must be recorded in the case report file. 2. Has had a diagnosis of rheumatoid arthritis. 3. Individual has a condition the study physician believes would interfere with the participant's ability to provide informed consent, comply with his responsibilities during the study, which might confound the interpretation of the study results or put the person at undue risk. 4. Self-reported medical conditions including an active peptic ulcer, inflammatory bowel disease, or gastrointestinal bleeding and any medical condition or prior gastrointestinal surgery that could influence absorption, metabolism or excretion of the study supplement. 5. History or presence of significant, renal, hepatic, gastrointestinal, pulmonary,…