Internet Based Cognitive Behavioral Therapy in Pediatric Chronic Pancreatitis
CompletedNot applicableNCT03707431
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Abdominal pain is common in children with chronic and acute recurring pancreatitis (CP, ARP), and as they continue into adulthood, the disease progresses with increased pain and greater exposure to opioids. Despite the relevancy of early pain self-management for childhood pancreatitis, there have been no studies of non-pharmacological pain intervention in this population. The proposed project will evaluate a web-based cognitive behavioral pain management program delivered to a cohort of well-phenotyped children with CP/ARP and some community participants to reduce pain, pain-related disability and enhance HRQOL; it will also identify genetic risk factors and clinical and behavioral phenotypic factors associated with treatment response to enable precision medicine approaches.
Study details
- Official title
- A Randomized Trial of a Web-based Non-pharmacological Pain Intervention for Pediatric Chronic Pancreatitis
- Conditions
- Chronic Pancreatitis
- Acute Recurrent Pancreatitis
- Interventions
- Behavioral: Web-based CBT
- Behavioral: Pain Education
- Sponsor
- Seattle Children's Hospital
- Collaborators
- University of Iowa; University of Virginia; Washington University School of Medicine; M.D. Anderson Cancer Center; The University of Texas Health Science Center, Houston; Children's Hospital Medical Center, Cincinnati; Children's Hospital Los Angeles; Children's Hospital of Philadelphia; University of Toronto; McGill University Health Centre/Research Institute of the McGill University Health Centre; Medical College of Wisconsin; Massachusetts General Hospital; University of Minnesota; Ohio State University; University of Pittsburgh; University of California, San Francisco; University of Utah; Indiana University; Sydney Children's Hospitals Network; Cedars-Sinai Medical Center; Stanford University; Ariel Precision Medicine; University of Texas Southwestern Medical Center
- Start date
- 2019-04-25
- Primary completion
- 2024-07-31
- Sex
- All
- Age range
- from 10 Years to 19 Years
- Results posted
- Yes, on ClinicalTrials.gov
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: 1. Diagnosed with CP or ARP 2. ages 10-19 years 3. at least 4 acute pancreatitis flare-ups/attacks in past year, or at least 1 instance of moderate (4/10 pain) pancreatitis/abdominal pain in the past month 4. access to the Internet on any web-enabled device Exclusion criteria: 1. non-English speaking 2. inability to read at the 5th grade level due to learning problem or developmental delay 3. children with cystic fibrosis who have pancreatic insufficiency at the time of diagnosis 4. patients with Shwachman-Bodian-Diamond Syndrome 5. Acute Recurrent Pancreatitis (ARP) with no evidence of chronic or persistent pain 6. anticipated surgery (TPIAT or other) during study participation
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT03707431